Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A36182 | 18802068 | J Immunol | Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. | 2008 | Details |
| A36185 | 18795699 | Hepatogastroenterology | Surgically resected hepatocellular carcinomas in patients with non-alcoholic steatohepatitis. | 2009 | Details |
| A36201 | 18761681 | Hepatol Res | Assessment of hepatic steatosis and hepatic tissue blood flow by xenon computed tomography in nonalcoholic steatohepatitis. | 2008 | Details |
| A36214 | 18718471 | Gastroenterology | Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis. | 2008 | Details |
| A36237 | 18666257 | Hepatology | Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice. | 2008 | Details |
| A36238 | 18666236 | Hepatology | Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. | 2008 | Details |
| A36253 | 18636507 | IUBMB Life | Thioredoxin and thioredoxin binding protein 2 in the liver. | 2008 | Details |
| A36260 | 18609744 | J Rheumatol | Drug use and toxicity in psoriatic disease: focus on methotrexate. | 2008 | Details |
| A36270 | 18571789 | Hepatology | Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis. | 2008 | Details |
| A36272 | 18563978 | Rev Esp Enferm Dig | [Gene expression in obese patients with non-alcoholic steatohepatitis]. | 2008 | Details |
| A36291 | 18513333 | Hepatol Res | Bezafibrate prevents hepatic stellate cell activation and fibrogenesis in a murine steatohepatitis model, and suppresses fibrogenic response induced by transforming growth factor-beta1 in a cultured stellate cell line. | 2008 | Details |
| A36297 | 18503774 | Gastroenterology | Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial. | 2008 | Details |
| A36319 | 18467911 | Eur J Gastroenterol Hepatol | Bile acid levels are increased in the liver of patients with steatohepatitis. | 2008 | Details |
| A36320 | 18465233 | Dig Dis Sci | Effects of a long-term high-fat diet and switching from a high-fat to low-fat, standard diet on hepatic fat accumulation in Sprague-Dawley rats. | 2008 | Details |
| A36323 | 18459024 | Obes Surg | Fatty liver disease: predictors of nonalcoholic steatohepatitis and gallbladder disease in morbid obesity. | 2008 | Details |
| A36324 | 18458846 | J Gastroenterol | Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells. | 2008 | Details |
| A36341 | 18408102 | Gut | Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis. | 2008 | Details |
| A36343 | 18403495 | Gut | Serum proteomic profiling of obese patients: correlation with liver pathology and evolution after bariatric surgery. | 2008 | Details |
| A36348 | 18392239 | J Gastrointestin Liver Dis | Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet. | 2008 | Details |
| A36384 | 18328071 | Hepatol Res | Prevalence of esophagogastric varices in patients with non-alcoholic steatohepatitis. | 2008 | Details |
| A36404 | 18277895 | J Clin Gastroenterol | Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis. | 2008 | Details |
| A36413 | 18239988 | Wien Klin Wochenschr | Differentiation of nonalcoholic from alcoholic steatohepatitis: are routine laboratory markers useful? | 2008 | Details |
| A36428 | 18228197 | Histol Histopathol | Presence of perivenular elastic fibers in nonalcoholic steatohepatitis Fibrosis Stage III. | 2008 | Details |
| A36431 | 18226970 | Surg Obes Relat Dis | Predictors of nonalcoholic steatohepatitis in patients undergoing bariatric surgery: when is liver biopsy indicated? | 2008 | Details |
| A36439 | 18197877 | Hepatol Res | Combination of N-acetylcysteine and metformin improves histological steatosis and fibrosis in patients with non-alcoholic steatohepatitis. | 2008 | Details |
| A36476 | 18049900 | Dig Dis Sci | Liver histology changes in nonalcoholic steatohepatitis after one year of treatment with probucol. | 2007 | Details |
| A36482 | 18042441 | J Cyst Fibros | A single centre experience of liver disease in adults with cystic fibrosis 1995-2006. | 2007 | Details |
| A36487 | 18029322 | Adv Ther | Correlation of serum adiponectin levels and hepatic steatosis in hepatitis C virus genotype 1 infection. | 2008 | Details |
| A36492 | 18000880 | Hepatology | Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis. | 2008 | Details |
| A36493 | 18000736 | Obes Surg | Effect of high fat diet on the volume of liver and quantitative feature of Kupffer cells in the female rat: a stereological and ultrastructural study. | 2007 | Details |
| A36504 | 17973959 | Am J Transplant | Cystic fibrosis liver disease: to transplant or not to transplant? | 2007 | Details |
| A36511 | 17963695 | Biochem Biophys Res Commun | Telmisartan prevents hepatic fibrosis and enzyme-altered lesions in liver cirrhosis rat induced by a choline-deficient L-amino acid-defined diet. | 2007 | Details |
| A36516 | 17947452 | Am J Physiol Gastrointest Liver Physiol | A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet. | 2007 | Details |
| A36534 | 17929294 | Hepatology | Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. | 2007 | Details |
| A36543 | 17892356 | Expert Rev Mol Diagn | FibroMAX: towards a new universal biomarker of liver disease? | 2007 | Details |
| A36551 | 17873605 | Eur J Gastroenterol Hepatol | Primary liver cancers with nonalcoholic steatohepatitis. | 2007 | Details |
| A36562 | 17825453 | J Hepatol | Iron preloading aggravates nutritional steatohepatitis in rats by increasing apoptotic cell death. | 2007 | Details |
| A36576 | 17710676 | Scand J Gastroenterol | Importance of cytokines, oxidative stress and expression of BCL-2 in the pathogenesis of non-alcoholic steatohepatitis. | 2007 | Details |
| A36582 | 17690174 | Am J Physiol Gastrointest Liver Physiol | Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver. | 2007 | Details |
| A36584 | 17680648 | Hepatology | HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis. | 2007 | Details |
| A36598 | 17659580 | Hepatology | Evidence for a role of nonalcoholic steatohepatitis in hepatitis C: a prospective study. | 2007 | Details |
| A36600 | 17654603 | Hepatology | Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C. | 2007 | Details |
| A36606 | 17631134 | Gastroenterology | Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. | 2007 | Details |
| A36613 | 17610504 | Hepatol Res | Influence of age and gender in Japanese patients with non-alcoholic steatohepatitis. | 2007 | Details |
| A36614 | 17610502 | Hepatol Res | Combined pantethine and probucol therapy for Japanese patients with non-alcoholic steatohepatitis. | 2007 | Details |
| A36634 | 17565640 | J Gastroenterol Hepatol | Effect of losartan on early liver fibrosis development in a rat model of nonalcoholic steatohepatitis. | 2007 | Details |
| A36637 | 17559148 | Hepatology | The effects of discontinuing pioglitazone in patients with nonalcoholic steatohepatitis. | 2007 | Details |
| A36648 | 17530362 | J Gastroenterol | Type IV collagen 7s domain is an independent clinical marker of the severity of fibrosis in patients with nonalcoholic steatohepatitis before the cirrhotic stage. | 2007 | Details |
| A36654 | 17518368 | Hepatology | Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis. | 2007 | Details |
| A36672 | 17483780 | Gastroenterol Clin Biol | [Steatosis, chronic hepatitis virus C infection and homocysteine]. | 2007 | Details |
| A36688 | 17459514 | J Hepatol | Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model. | 2007 | Details |
| A36702 | 17429733 | Dig Dis Sci | The serum endothelin-1 level in steatosis and NASH, and its relation with severity of liver fibrosis. | 2007 | Details |
| A36704 | 17420940 | Dig Dis Sci | Protective effect of soy isoflavones and activity levels of plasma paraoxonase and arylesterase in the experimental nonalcoholic steatohepatitis model. | 2007 | Details |
| A36707 | 17415655 | Dig Dis Sci | Amelioration of steatohepatitis with pentoxifylline in a novel nonalcoholic steatohepatitis model induced by high-fat diet. | 2007 | Details |
| A36710 | 17410441 | Dig Dis Sci | Telmisartan, an angiotensin II type 1 receptor blocker, controls progress of nonalcoholic steatohepatitis in rats. | 2007 | Details |
| A36711 | 17410287 | J Gastrointestin Liver Dis | Therapeutic options in non-alcoholic steatohepatitis (NASH). Are all agents alike? Results of a preliminary study. | 2007 | Details |
| A36714 | 17404856 | Dig Dis Sci | Orlistat reverse fatty infiltration and improves hepatic fibrosis in obese patients with nonalcoholic steatohepatitis (NASH). | 2007 | Details |
| A36722 | 17388862 | Intern Med J | Effects of vitamin E treatment on peroxisome proliferator-activated receptor-alpha expression and insulin resistance in patients with non-alcoholic steatohepatitis: results of a pilot study. | 2007 | Details |
| A36723 | 17385458 | Ter Arkh | [Outpatient clinic facilities for clinical-laboratory diagnosis of hepatic fibrosis]. | 2007 | Details |
| A36726 | 17379003 | Metabolism | Transgenic mice expressing nuclear sterol regulatory element-binding protein 1c in adipose tissue exhibit liver histology similar to nonalcoholic steatohepatitis. | 2007 | Details |
| A36742 | 17355768 | Obes Surg | Diagnostic value of ultrasonographic examination for nonalcoholic steatohepatitis in morbidly obese patients undergoing laparoscopic bariatric surgery. | 2007 | Details |
| A36745 | 17351431 | Invest Radiol | Potential of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for differential diagnosis of nonalcoholic steatohepatitis and fatty liver in rats using magnetic resonance imaging. | 2007 | Details |
| A36751 | 17335677 | Curr Gastroenterol Rep | Treatment of fibrosis in nonalcoholic fatty liver disease. | 2007 | Details |
| A36760 | 17322381 | Am J Pathol | Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis. | 2007 | Details |
| A36766 | 17311617 | Liver Int | Open-label pilot study of folic acid in patients with nonalcoholic steatohepatitis. | 2007 | Details |
| A36799 | 17244458 | Zhonghua Gan Zang Bing Za Zhi | [The role of apoptosis and the related genes in non-alcoholic steatohepatitis]. | 2007 | Details |
| A36801 | 17241878 | Gastroenterology | Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. | 2006 | Details |
| A36805 | 17229244 | Aliment Pharmacol Ther | Screening for liver disease using non-invasive biomarkers (FibroTest, SteatoTest and NashTest) in patients with hyperlipidaemia. | 2007 | Details |
| A36808 | 17217634 | Obes Surg | Hepatic histopathology of morbid obesity: concurrence of other forms of chronic liver disease. | 2006 | Details |
| A36836 | 17137680 | Rev Med Interne | [Results and place of Fibroscan in the non-invasive diagnosis of hepatic fibrosis]. | 2006 | Details |
| A36841 | 17128639 | Postgrad Med | Noninvasive tests for liver fibrosis. | 2006 | Details |
| A36848 | 17105586 | Liver Int | Values and limitations of serum aminotransferases in clinical trials of nonalcoholic steatohepatitis. | 2006 | Details |
| A36850 | 17101320 | Gastroenterology | Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C. | 2006 | Details |
| A36851 | 17086867 | Hepatogastroenterology | Usefulness of serum hepatic fibrosis markers in the diagnosis of nonalcoholic steatohepatitis (NASH). | 2007 | Details |
| A36860 | 17060319 | J Biol Chem | Impaired proteolysis of collagen I inhibits proliferation of hepatic stellate cells: implications for regulation of liver fibrosis. | 2006 | Details |
| A36872 | 17032406 | Liver Int | Increased expression of Ob-Rb and its relationship with the overexpression of TGF-beta1 and the stage of fibrosis in patients with nonalcoholic steatohepatitis. | 2006 | Details |
| A36886 | 17006938 | Hepatology | Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats. | 2006 | Details |
| A36893 | 16988759 | J Gastroenterol | Clinical features of nonalcoholic steatohepatitis in Japan: Evidence from the literature. | 2006 | Details |
| A36911 | 16958001 | Dig Dis Sci | Predictors of cirrhosis in Hispanic patients with nonalcoholic steatohepatitis. | 2006 | Details |
| A36912 | 16953841 | Liver Int | Quantitative trait loci analysis of mice administered the methionine-choline deficient dietary model of experimental steatohepatitis. | 2006 | Details |
| A36925 | 16936261 | Am J Pathol | A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury. | 2006 | Details |
| A36948 | 16890173 | Hepatol Res | Interobserver variation in the histopathological assessment of nonalcoholic steatohepatitis. | 2005 | Details |
| A36955 | 16868265 | Psychosom Med | Depression, anxiety, and nonalcoholic steatohepatitis. | 2008 | Details |
| A36959 | 16848812 | Am J Gastroenterol | Potential role of chitotriosidase gene in nonalcoholic fatty liver disease evolution. | 2006 | Details |
| A36963 | 16837098 | J Hepatol | Diagnostic and predictive factors of significant liver fibrosis and minimal lesions in patients with persistent unexplained elevated transaminases. A prospective multicenter study. | 2006 | Details |
| A36967 | 16814613 | Clin Gastroenterol Hepatol | Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. | 2006 | Details |
| A36987 | 16768127 | Nihon Rinsho | [NASH in children]. | 2006 | Details |
| A36988 | 16768126 | Nihon Rinsho | [NASH and metabolic syndrome]. | 2006 | Details |
| A36989 | 16768125 | Nihon Rinsho | [Insulin sensitizer--anti-diabetic drugs, metformin and pioglitazone that can improve insulin resistance]. | 2006 | Details |
| A36990 | 16768123 | Nihon Rinsho | [Drug therapy for non-alcoholic steatohepatitis]. | 2006 | Details |
| A36991 | 16768117 | Nihon Rinsho | [Non-alcoholic steatohepatitis : pathology and pathogenesis]. | 2006 | Details |
| A36992 | 16768116 | Nihon Rinsho | [Drug-induced NASH]. | 2006 | Details |
| A36995 | 16768113 | Nihon Rinsho | [Adipokine interrelationship with the liver]. | 2006 | Details |
| A37058 | 16554999 | Surg Today | Hepatocellular carcinoma arising from nonalcoholic steatohepatitis: report of two cases. | 2006 | Details |
| A37061 | 16546742 | Nan Fang Yi Ke Da Xue Xue Bao | [Nonalcoholic steatohepatitis: a clinicopathological analysis of liver biopsy in 32 cases]. | 2006 | Details |
| A37062 | 16540767 | J Clin Gastroenterol | Bariatric surgery: a promising solution for nonalcoholic steatohepatitis in the very obese. | 2006 | Details |
| A37068 | 16531962 | Ann Hepatol | Nonalcoholic steatohepatitis (NASH) with diabetes: predictors of liver fibrosis. | 2006 | Details |
| A37081 | 16672825 | J Clin Gastroenterol | Bariatric Surgery: A Promising Solution for Nonalcoholic Steatohepatitis in the Very Obese. | 2006 | Details |
| A37091 | 16498637 | J Biochem Mol Toxicol | Glutathione-enhancing agents protect against steatohepatitis in a dietary model. | 2006 | Details |
| A37093 | 16492691 | J Clin Endocrinol Metab | Nonalcoholic steatohepatitis and nonalcoholic Fatty liver disease in young women with polycystic ovary syndrome. | 2006 | Details |