Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Obesity11722 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02963 | 34183373 | Diabetes | Deletion of the Feeding-Induced Hepatokine TSK Ameliorates the Melanocortin Obesity Syndrome. | 2021 | Details |
| A02966 | 34182070 | Free Radic Biol Med | Ethnicity-specific alterations of plasma and hepatic lipidomic profiles are related to high NAFLD rate and severity in Hispanic Americans, a pilot study. | 2021 | Details |
| A02971 | 34178902 | Front Pediatr | Relationship Between Histological Features of Non-alcoholic Fatty Liver Disease and Ectopic Fat on Magnetic Resonance Imaging in Children and Adolescents. | 2021 | Details |
| A02972 | 34178303 | J Surg Case Rep | Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report. | 2021 | Details |
| A02973 | 34177920 | Front Immunol | Prebiotic Inulin and Sodium Butyrate Attenuate Obesity-Induced Intestinal Barrier Dysfunction by Induction of Antimicrobial Peptides. | 2021 | Details |
| A02975 | 34176541 | Br J Nutr | Sex influences the association between appendicular skeletal muscle mass to visceral fat area ratio and non-alcoholic steatohepatitis in patients with biopsy-proven non-alcoholic fatty liver disease. | 2021 | Details |
| A02983 | 34174062 | J Gastrointestin Liver Dis | The Leu72Met (rs696217 G>T) Polymorphism of the Ghrelin Gene Might Be a Protective Factor for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02993 | 34171462 | Biochim Biophys Acta Gene Regul Mech | Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding. | 2021 | Details |
| A02994 | 34171418 | Food Chem Toxicol | Palmitoyl-CoA effect on cytochrome c release, a key process of apoptosis, from liver mitochondria of rat with sucrose diet-induced obesity. | 2021 | Details |
| A02995 | 34171397 | J Ethnopharmacol | Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway. | 2021 | Details |
| A02996 | 34171051 | Rom J Morphol Embryol | Pediatric nonalcoholic fatty liver disease - a changing diagnostic paradigm. | 2021 | Details |
| A03000 | 34169247 | JHEP Rep | Hepatic microbiome in healthy lean and obese humans. | 2021 | Details |
| A03001 | 34168615 | Front Endocrinol (Lausanne) | Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome. | 2021 | Details |
| A03004 | 34168277 | Int J Obes (Lond) | Performance of non-invasive fibrosis scores in non-alcoholic fatty liver disease with and without morbid obesity. | 2021 | Details |
| A03005 | 34168043 | BMJ Open Gastroenterol | Exercising in the COVID-19 era: implications in non-alcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A03006 | 34167531 | BMC Surg | Bariatric surgery for non-alcoholic fatty liver disease in individuals with obesity (Base-NAFLD): protocol of a prospective multicenter observational follow-up study. | 2021 | Details |
| A03008 | 34165645 | J Med Ultrason (2001) | Attenuation coefficient (ATT) measurement for liver fat quantification in chronic liver disease. | 2021 | Details |
| A03015 | 34163108 | World J Gastroenterol | Clinical indicators for progression of nonalcoholic steatohepatitis to cirrhosis. | 2021 | Details |
| A03016 | 34162924 | Sci Rep | Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation. | 2021 | Details |
| A03033 | 34156590 | Dig Dis Sci | A Decreased Response to Resistin in Mononuclear Leukocytes Contributes to Oxidative Stress in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03037 | 34155821 | Pediatr Obes | Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity. | 2021 | Details |
| A03038 | 34155801 | Liver Int | Management of NAFLD patients with advanced fibrosis. | 2021 | Details |
| A03039 | 34155799 | Liver Int | Current management of NAFLD/NASH. | 2021 | Details |
| A03040 | 34155798 | Liver Int | Non-alcoholic fatty liver disease in type 2 diabetes - A specific entity? | 2021 | Details |
| A03041 | 34155794 | Liver Int | New drugs for NASH. | 2021 | Details |
| A03043 | 34155789 | Liver Int | COVID-19 and the liver - Lessons learned. | 2021 | Details |
| A03067 | 34144391 | Redox Biol | Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules. | 2021 | Details |
| A03070 | 34142516 | J Pediatr Endocrinol Metab | Evaluation of clinical, endocrine and metabolic findings in obese children with and without hepatosteatosis. | 2021 | Details |
| A03074 | 34141776 | World J Clin Cases | Nonalcoholic fatty liver disease and COVID-19: An epidemic that begets pandemic. | 2021 | Details |
| A03075 | 34141709 | Front Cell Dev Biol | New Insights Into the Role of Autophagy in Liver Surgery in the Setting of Metabolic Syndrome and Related Diseases. | 2021 | Details |
| A03078 | 34139486 | ESMO Open | Cancer and hepatic steatosis. | 2021 | Details |
| A03085 | 34136549 | Front Cardiovasc Med | The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients. | 2021 | Details |
| A03088 | 34136163 | Food Sci Nutr | Effects of several tea extracts on nonalcoholic fatty liver disease in mice fed with a high-fat diet. | 2021 | Details |
| A03093 | 34134495 | Cas Lek Cesk | Non-alcoholic fatty liver disease - how to effectively fight the nowadays most common liver disease? | 2021 | Details |
| A03100 | 34131333 | Nat Rev Endocrinol | Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus. | 2021 | Details |
| A03110 | 34126247 | Endocr Pract | High Prevalence of Nonalcoholic Fatty Liver Disease Among Adolescents and Young Adults With Hypopituitarism due to Growth Hormone Deficiency. | 2021 | Details |
| A03113 | 34125886 | J Clin Endocrinol Metab | New Nonalcoholic Fatty Liver Disease and Fibrosis Progression Associate With the Risk of Incident Chronic Kidney Disease. | 2021 | Details |
| A03114 | 34125646 | Gut Microbes | Desulfovibrio vulgaris, a potent acetic acid-producing bacterium, attenuates nonalcoholic fatty liver disease in mice. | 2021 | Details |
| A03116 | 34124059 | Front Cell Dev Biol | Pathological Crosstalk Between Oxidized LDL and ER Stress in Human Diseases: A Comprehensive Review. | 2021 | Details |
| A03123 | 34120339 | Eur J Clin Invest | Nonalcoholic fatty liver disease, circulating ketone bodies and all-cause mortality in a general population-based cohort. | 2021 | Details |
| A03127 | 34119629 | J Nutr Biochem | Sugar kelp (Saccharina latissima) inhibits hepatic inflammation and fibrosis in a mouse model of diet-induced nonalcoholic steatohepatitis. | 2021 | Details |
| A03131 | 34118476 | Mol Metab | Exercise of high intensity ameliorates hepatic inflammation and the progression of NASH. | 2021 | Details |
| A03132 | 34118361 | Peptides | A synthetic peptide AWRK6 ameliorates metabolic associated fatty liver disease: involvement of lipid and glucose homeostasis. | 2021 | Details |
| A03136 | 34118015 | Updates Surg | Liver transplantation and bariatric surgery: a new surgical reality: a systematic review of the best time for bariatric surgery. | 2021 | Details |
| A03146 | 34114325 | EMBO Rep | SCFJFK is functionally linked to obesity and metabolic syndrome. | 2021 | Details |
| A03147 | 34113839 | JHEP Rep | Evaluating causality of cellular senescence in non-alcoholic fatty liver disease. | 2021 | Details |
| A03152 | 34112075 | Kardiologiia | Early cardiac electrical and structural changes in patients with non-obese non-alcoholic fatty liver disease. | 2021 | Details |
| A03157 | 34107897 | BMC Pediatr | Prevalence of increased transaminases and its association with sex, age, and metabolic parameters in children and adolescents with obesity - a nationwide cross-sectional cohort study. | 2021 | Details |
| A03163 | 34106786 | Am J Physiol Cell Physiol | Impaired Ca2+ signaling due to hepatic steatosis mediates hepatic insulin resistance in Alström syndrome mice that is reversed by GLP-1 analog treatment. | 2021 | Details |
| A03166 | 34106515 | Clin Obes | A clinical model to predict fibrosis on liver biopsy in paediatric subjects with nonalcoholic fatty liver disease. | 2021 | Details |
| A03172 | 34103552 | Sci Rep | Cross-sectional pilot study to assess primary healthcare workers' knowledge of nonalcoholic fatty liver disease in a marginalized community in Mexico. | 2021 | Details |
| A03175 | 34100658 | Clin Pediatr (Phila) | Serum Alanine Transaminase Is an Inadequate Nonalcoholic Fatty Liver Screening Test in Adolescents: Results From the National Health and Nutrition Examination Survey 2017-2018. | 2021 | Details |
| A03176 | 34099626 | Nutr Diabetes | Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner. | 2021 | Details |
| A03181 | 34097961 | Int J Biol Macromol | A homogeneous polysaccharide from Lycium barbarum: Structural characterizations, anti-obesity effects and impacts on gut microbiota. | 2021 | Details |
| A03183 | 34096925 | J Vis Exp | A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium. | 2021 | Details |
| A03186 | 34095739 | J Pancreat Cancer | Nonalcoholic Fatty Liver Disease After Pancreaticoduodenectomy for a Cancer Diagnosis. | 2021 | Details |
| A03190 | 34095164 | Front Med (Lausanne) | Age and Interleukin-15 Levels Are Independently Associated With Intima-Media Thickness in Obesity-Related NAFLD Patients. | 2021 | Details |
| A03202 | 34091530 | Chin Med J (Engl) | Cardiovascular and renal burdens of metabolic associated fatty liver disease from serial US national surveys, 1999-2016. | 2021 | Details |
| A03203 | 34091049 | Clin Gastroenterol Hepatol | A Polygenic Risk Score to Refine Risk Stratification and Prediction for Severe Liver Disease by Clinical Fibrosis Scores. | 2021 | Details |
| A03211 | 34088709 | BMJ Open | Is there scope to improve the selection of patients with alcohol-related liver disease for referral to secondary care? A retrospective analysis of primary care referrals to a UK liver centre, incorporating simple blood tests. | 2021 | Details |
| A03219 | 34083525 | Nat Commun | Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance. | 2021 | Details |
| A03224 | 34081733 | PLoS One | Prevalence and factors associated with NAFLD detected by vibration controlled transient elastography among US adults: Results from NHANES 2017-2018. | 2021 | Details |
| A03225 | 34081362 | J Intern Med | Pulmonary hypertension is associated with an increased incidence of NAFLD: A retrospective cohort study of 18,910 patients. | 2021 | Details |
| A03231 | 34078528 | BMB Rep | Porphyromonas gingivalis exacerbates the progression of fatty liver disease via CD36-PPARγ pathway. | 2021 | Details |
| A03235 | 34077443 | PLoS One | Severity of non-alcoholic steatohepatitis is not linked to testosterone concentration in patients with type 2 diabetes. | 2021 | Details |
| A03242 | 34074100 | Vnitr Lek | Rheumatoid arthritis and metabolic disorders. | 2021 | Details |
| A03244 | 34073883 | J Clin Med | Decreased Muscle-to-Fat Mass Ratio Is Associated with Low Muscular Fitness and High Alanine Aminotransferase in Children and Adolescent Boys in Organized Sports Clubs. | 2021 | Details |
| A03245 | 34073834 | Int J Mol Sci | P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice. | 2021 | Details |
| A03246 | 34072995 | Metabolites | Gut Microbiome and Metabolites in Patients with NAFLD and after Bariatric Surgery: A Comprehensive Review. | 2021 | Details |
| A03250 | 34072137 | Nutrients | Effect of Dietary Fatty Acids on MicroRNA Expression Related to Metabolic Disorders and Inflammation in Human and Animal Trials. | 2021 | Details |
| A03255 | 34069390 | Cells | Maternal Exercise Mediates Hepatic Metabolic Programming via Activation of AMPK-PGC1α Axis in the Offspring of Obese Mothers. | 2021 | Details |
| A03257 | 34069012 | Int J Environ Res Public Health | Non-Alcoholic Fatty Liver Disease: Metabolic, Genetic, Epigenetic and Environmental Risk Factors. | 2021 | Details |
| A03264 | 34065978 | Nutrients | PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity. | 2021 | Details |
| A03268 | 34065241 | Biology (Basel) | Treating the Metabolic Syndrome by Fecal Transplantation-Current Status. | 2021 | Details |
| A03270 | 34065140 | Children (Basel) | Update on Metabolic Bariatric Surgery for Morbidly Obese Adolescents. | 2021 | Details |
| A03271 | 34065108 | Int J Mol Sci | Metformin Actions on the Liver: Protection Mechanisms Emerging in Hepatocytes and Immune Cells against NASH-Related HCC. | 2021 | Details |
| A03277 | 34064337 | J Clin Med | Correlation between Liver Stiffness by Two-Dimensional Shear Wave Elastography and Waist Circumference in Japanese Local Citizens with Abdominal Obesity. | 2021 | Details |
| A03279 | 34063472 | Int J Mol Sci | The Potential Protective Role of RUNX1 in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03280 | 34062716 | Int J Mol Sci | Role of Endocrine-Disrupting Chemicals in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review. | 2021 | Details |
| A03281 | 34062584 | Dtsch Med Wochenschr | [Alpha-1 antitrypsin deficiency: cause and cofactor for liver disease]. | 2021 | Details |
| A03285 | 34060951 | Endocr Res | AST-120 Treatment Alters the Gut Microbiota Composition and Suppresses Hepatic Triglyceride Levels in Obese Mice. | 2021 | Details |
| A03287 | 34060475 | J Endocrinol | DHT causes liver steatosis via transcriptional regulation of SCAP in normal weight female mice. | 2021 | Details |
| A03288 | 34059777 | Eur J Clin Nutr | Joint associations of adiposity and alcohol consumption with liver disease-related morbidity and mortality risk: findings from the UK Biobank. | 2021 | Details |
| A03293 | 34058074 | FEBS J | Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts. | 2021 | Details |
| A03299 | 34054728 | Front Endocrinol (Lausanne) | Serum Uric Acid Is a Mediator of the Association Between Obesity and Incident Nonalcoholic Fatty Liver Disease: A Prospective Cohort Study. | 2021 | Details |
| A03304 | 34051210 | Biochem Pharmacol | The controversy on the beneficial effect of phytoestrogens in diabetic treatment in postmenopausal women. | 2021 | Details |
| A03329 | 34043121 | Dig Dis Sci | Disease Knowledge, Health-Related Quality of Life, and Lifestyle Behavior Change in Patients with Nonalcoholic Fatty Liver Disease: Impact of an Educational Intervention. | 2021 | Details |
| A03330 | 34041467 | JHEP Rep | A nationwide population-based prospective study of cirrhosis in Iceland. | 2021 | Details |
| A03332 | 34040583 | Front Endocrinol (Lausanne) | Gene-Environmental Interactions as Metabolic Drivers of Nonalcoholic Steatohepatitis. | 2021 | Details |
| A03334 | 34040322 | World J Gastroenterol | Individualized treatment options for patients with non-cirrhotic and cirrhotic liver disease. | 2021 | Details |
| A03335 | 34039490 | J Hepatol | The global burden of cirrhosis: A review of disability-adjusted life-years lost and unmet needs. | 2021 | Details |
| A03339 | 34036255 | JHEP Rep | Historical narrative from fatty liver in the nineteenth century to contemporary NAFLD - Reconciling the present with the past. | 2021 | Details |
| A03349 | 34032283 | Eur J Clin Invest | Multiplying effects of COVID-19 lockdown on metabolic risk and fatty liver. | 2021 | Details |
| A03354 | 34031327 | Med J Malaysia | Liver fibrosis associated with adipose tissue and liver inflammation in an obesity model. | 2021 | Details |
| A03355 | 34031143 | Diabetes Care | The Relationship Between Body Fat Distribution and Nonalcoholic Fatty Liver in Adults With Type 1 Diabetes. | 2021 | Details |
| A03357 | 34029949 | Biomed Pharmacother | The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model. | 2021 | Details |
| A03358 | 34029162 | Am J Physiol Endocrinol Metab | β2-Adrenergic receptor agonist induced hepatic steatosis in mice: modeling nonalcoholic fatty liver disease in hyperadrenergic states. | 2021 | Details |
| A03359 | 34028830 | Med J Aust | Prevalence of non-alcoholic fatty liver disease in regional Victoria: a prospective population-based study. | 2021 | Details |
| A03361 | 34027933 | Minerva Gastroenterol (Torino) | The role of elastography in non-alcoholic fatty liver disease. | 2021 | Details |
| A03362 | 34027591 | Dig Dis Sci | Hepatocellular Carcinoma in Patients Without Cirrhosis: The Fibrosis Stage Distribution, Characteristics and Survival. | 2021 | Details |