Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09653 | 31657510 | Mol Nutr Food Res | The Buckwheat Iminosugar d-Fagomine Attenuates Sucrose-Induced Steatosis and Hypertension in Rats. | 2019 | Details |
| A09667 | 31652839 | Int J Mol Sci | The Crosstalk of miRNA and Oxidative Stress in the Liver: From Physiology to Pathology and Clinical Implications. | 2019 | Details |
| A09672 | 31652524 | Animals (Basel) | The Anti-Oxidation and Mechanism of Essential Oil of Paederia scandens in the NAFLD Model of Chicken. | 2019 | Details |
| A09686 | 31648561 | FASEB J | KLF15-activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF-κB-FGF21 or SREBP1c-FGF21 pathway. | 2019 | Details |
| A09690 | 31646583 | Eur Rev Med Pharmacol Sci | Key molecular pathways in the progression of non-alcoholic steatohepatitis. | 2019 | Details |
| A09701 | 31640183 | Nutrients | Water Extract of Curcuma longa L. Ameliorates Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09728 | 31632961 | Front Cell Dev Biol | NFκB/Orai1 Facilitates Endoplasmic Reticulum Stress by Oxidative Stress in the Pathogenesis of Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09734 | 31632109 | Diabetes Metab Syndr Obes | Plant-derived oleanolic acid ameliorates markers associated with non-alcoholic fatty liver disease in a diet-induced pre-diabetes rat model. | 2019 | Details |
| A09770 | 31616668 | Front Med (Lausanne) | Cardiovascular Risk in Fatty Liver Disease: The Liver-Heart Axis-Literature Review. | 2019 | Details |
| A09775 | 31614673 | Cells | Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells. | 2019 | Details |
| A09777 | 31614639 | Biomolecules | Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. | 2019 | Details |
| A09779 | 31614491 | Int J Mol Sci | Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products. | 2019 | Details |
| A09787 | 31610178 | Am J Pathol | Ferroptosis Affects the Progression of Nonalcoholic Steatohepatitis via the Modulation of Lipid Peroxidation-Mediated Cell Death in Mice. | 2019 | Details |
| A09796 | 31607566 | Dig Liver Dis | L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. | 2019 | Details |
| A09798 | 31606352 | Ann Hepatol | Chronic kidney disease in patients with non-alcoholic fatty liver disease: What the Hepatologist should know? | 2019 | Details |
| A09799 | 31605031 | Nat Rev Gastroenterol Hepatol | Adaptive immunity: an emerging player in the progression of NAFLD. | 2019 | Details |
| A09805 | 31604029 | Am J Physiol Gastrointest Liver Physiol | Intermittent restraint-induced sympathetic activation attenuates hepatic steatosis and inflammation in a high-fat diet-fed mouse model. | 2019 | Details |
| A09834 | 31595236 | Porto Biomed J | Dietary cholesterol does not break your heart but kills your liver. | 2019 | Details |
| A09859 | 31589122 | Curr Drug Targets | Natural Aldose Reductase Inhibitor: A Potential Therapeutic Agent for Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A09876 | 31578240 | Sci Transl Med | Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates. | 2019 | Details |
| A09894 | 31571145 | Arch Pharm Res | Molecular insights into the role of mitochondria in non-alcoholic fatty liver disease. | 2019 | Details |
| A09917 | 31561285 | FEBS Open Bio | Inhibition of sodium-glucose cotransporter 2 ameliorates renal injury in a novel medaka model of nonalcoholic steatohepatitis-related kidney disease. | 2019 | Details |
| A09937 | 31554274 | Int J Environ Res Public Health | Overview of the Pathogenesis, Genetic, and Non-Invasive Clinical, Biochemical, and Scoring Methods in the Assessment of NAFLD. | 2019 | Details |
| A09970 | 31540081 | Nutrients | Dietary Supplementation with Hazelnut Oil Reduces Serum Hyperlipidemia and Ameliorates the Progression of Nonalcoholic Fatty Liver Disease in Hamsters Fed a High-Cholesterol Diet. | 2019 | Details |
| A09998 | 31531097 | Iran J Pathol | The Correlation between Serum Zinc Level and Liver Histology in Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A10030 | 31519174 | BMC Complement Altern Med | Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells. | 2019 | Details |
| A10049 | 31514051 | Redox Biol | Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function. | 2019 | Details |
| A10063 | 31505325 | Redox Biol | Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase signaling. | 2019 | Details |
| A10073 | 31501836 | Food Funct | High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration. | 2019 | Details |
| A10087 | 31493247 | Hormones (Athens) | Selenium and selenoprotein P in nonalcoholic fatty liver disease. | 2019 | Details |
| A10088 | 31492960 | Sci Rep | Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease. | 2019 | Details |
| A10090 | 31491949 | Int J Mol Sci | Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis. | 2019 | Details |
| A10091 | 31491605 | Ecotoxicol Environ Saf | Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells. | 2019 | Details |
| A10096 | 31488034 | Am J Chin Med | Rhus verniciflua and Eucommia ulmoides Protects Against High-Fat Diet-Induced Hepatic Steatosis by Enhancing Anti-Oxidation and AMPK Activation. | 2019 | Details |
| A10099 | 31484323 | Nutrients | Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress. | 2019 | Details |
| A10115 | 31477174 | Stem Cell Res Ther | Antioxidant-upregulated mesenchymal stem cells reduce inflammation and improve fatty liver disease in diet-induced obesity. | 2019 | Details |
| A10117 | 31475569 | Arch Physiol Biochem | Inactivation of the superoxide dismutase by malondialdehyde in the nonalcoholic fatty liver disease: a combined molecular docking approach to clinical studies. | 2019 | Details |
| A10122 | 31474685 | J Nutr Sci Vitaminol (Tokyo) | Age-Related Alterations of Nonalcoholic Steatohepatitis in Sprague-Dawley Rats Fed a High-Fat and High-Cholesterol Diet. | 2019 | Details |
| A10139 | 31470786 | Curr Pharm Des | A Mitochondrial Approach to Cardiovascular Risk and Disease. | 2019 | Details |
| A10142 | 31470518 | Biomolecules | Beyond the Scavenging of Reactive Oxygen Species (ROS): Direct Effect of Cerium Oxide Nanoparticles in Reducing Fatty Acids Content in an In Vitro Model of Hepatocellular Steatosis. | 2019 | Details |
| A10154 | 31466361 | Int J Environ Res Public Health | Chemical Effect of Bisphenol A on Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10168 | 31460584 | Arq Gastroenterol | N-ACETYLCYSTEINE AND/OR URSODEOXYCHOLIC ACID ASSOCIATED WITH METFORMIN IN NON-ALCOHOLIC STEATOHEPATITIS: AN OPEN-LABEL MULTICENTER RANDOMIZED CONTROLLED TRIAL. | 2019 | Details |
| A10175 | 31452288 | Phytother Res | Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice. | 2019 | Details |
| A10177 | 31450746 | Toxins (Basel) | Chronic Low Dose Oral Exposure to Microcystin-LR Exacerbates Hepatic Injury in a Murine Model of Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10210 | 31430977 | Int J Mol Sci | Paraoxonase-1 as a Regulator of Glucose and Lipid Homeostasis: Impact on the Onset and Progression of Metabolic Disorders. | 2019 | Details |
| A10212 | 31430456 | Eur J Pharmacol | Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells. | 2019 | Details |
| A10215 | 31428351 | Food Sci Nutr | Lactobacillus paracasei Jlus66 extenuate oxidative stress and inflammation via regulation of intestinal flora in rats with non alcoholic fatty liver disease. | 2019 | Details |
| A10218 | 31426291 | Int J Mol Sci | Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease. | 2019 | Details |
| A10220 | 31425956 | Diabetes Metab Syndr | A review of synbiotic efficacy in non-alcoholic fatty liver disease as a therapeutic approach. | 2019 | Details |
| A10223 | 31422074 | Arch Biochem Biophys | CRISPR Cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation. | 2019 | Details |
| A10229 | 31420528 | J Pharmacol Exp Ther | Withaferin A Improves Nonalcoholic Steatohepatitis in Mice. | 2019 | Details |
| A10239 | 31417486 | Front Neurol | Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration. | 2019 | Details |
| A10240 | 31415794 | Mol Cell Endocrinol | Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH). | 2019 | Details |
| A10250 | 31411894 | Am J Physiol Gastrointest Liver Physiol | Digoxin improves steatohepatitis with differential involvement of liver cell subsets in mice through inhibition of PKM2 transactivation. | 2019 | Details |
| A10279 | 31401392 | Biomed Pharmacother | Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice. | 2019 | Details |
| A10299 | 31393851 | J Clin Invest | Degradation of splicing factor SRSF3 contributes to progressive liver disease. | 2019 | Details |
| A10300 | 31393787 | Am J Physiol Gastrointest Liver Physiol | Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21. | 2019 | Details |
| A10304 | 31392349 | Cell Mol Life Sci | Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ pathways. | 2019 | Details |
| A10326 | 31387260 | Antioxidants (Basel) | Inhibition of Heme Oxygenase Antioxidant Activity Exacerbates Hepatic Steatosis and Fibrosis In Vitro. | 2019 | Details |
| A10327 | 31387232 | Int J Environ Res Public Health | DNA Hydroxymethylation at the Interface of the Environment and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10329 | 31387169 | Biomed Pharmacother | Mitochondrial dysfunction in high-fat diet-induced nonalcoholic fatty liver disease: The alleviating effect and its mechanism of Polygonatum kingianum. | 2019 | Details |
| A10337 | 31384535 | Acta Pharm Sin B | Silibinin ameliorates hepatic lipid accumulation and oxidative stress in mice with non-alcoholic steatohepatitis by regulating CFLAR-JNK pathway. | 2019 | Details |
| A10360 | 31375010 | Int J Environ Res Public Health | Novel Insights into the Genetic Landscape of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10361 | 31374969 | Nutrients | Melon GliSODin® Prevents Diet-Induced NASH Onset by Reducing Fat Synthesis and Improving Liver Function. | 2019 | Details |
| A10375 | 31366865 | Biol Pharm Bull | Cranberry Attenuates Progression of Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice. | 2019 | Details |
| A10379 | 31364723 | Int J Mol Med | Green tea polyphenols attenuate hepatic steatosis, and reduce insulin resistance and inflammation in high-fat diet-induced rats. | 2019 | Details |
| A10425 | 31341532 | Oxid Med Cell Longev | Dietary Glycotoxins Impair Hepatic Lipidemic Profile in Diet-Induced Obese Rats Causing Hepatic Oxidative Stress and Insulin Resistance. | 2019 | Details |
| A10453 | 31330977 | Antioxidants (Basel) | Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review. | 2019 | Details |
| A10458 | 31328113 | Prev Nutr Food Sci | Health Benefits of Carotenoids: A Role of Carotenoids in the Prevention of Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10484 | 31316716 | Oxid Med Cell Longev | Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model. | 2019 | Details |
| A10514 | 31307592 | Adv Pharmacol | Drug-induced liver injury in obesity and nonalcoholic fatty liver disease. | 2019 | Details |
| A10589 | 31279739 | Metabolism | Laparoscopic sleeve gastrectomy reverses non-alcoholic fatty liver disease modulating oxidative stress and inflammation. | 2019 | Details |
| A10599 | 31275421 | Evid Based Complement Alternat Med | The Combination of Mulberry Extracts and Silk Amino Acids Alleviated High Fat Diet-Induced Nonalcoholic Hepatic Steatosis by Improving Hepatic Insulin Signaling and Normalizing Gut Microbiome Dysbiosis in Rats. | 2019 | Details |
| A10601 | 31275407 | Evid Based Complement Alternat Med | Pharmacological Activities of Alisma orientale against Nonalcoholic Fatty Liver Disease and Metabolic Syndrome: Literature Review. | 2019 | Details |
| A10627 | 31265967 | Nutrition | Creatine supplementation exacerbates ethanol-induced hepatic damage in mice. | 2019 | Details |
| A10648 | 31255630 | Dig Liver Dis | Contribution of a genetic risk score to clinical prediction of hepatic steatosis in obese children and adolescents. | 2019 | Details |
| A10669 | 31244392 | Biosci Biotechnol Biochem | Extracts of bilberry (Vaccinium myrtillus L.) fruits improve liver steatosis and injury in mice by preventing lipid accumulation and cell death. | 2019 | Details |
| A10676 | 31241045 | Gen Physiol Biophys | Effect of glucagon-like peptide-1 analogue liraglutide on primary cultures of rat hepatocytes isolated from lean and steatotic livers. | 2019 | Details |
| A10689 | 31235166 | Diabetes Metab Syndr | A narrative review on effects of vitamin D on main risk factors and severity of Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A10692 | 31234658 | Free Radic Res | Oxidative stress biomarkers in the serum and plasma of patients with non-alcoholic fatty liver disease (NAFLD). Can plasma AGE be a marker of NAFLD? Oxidative stress biomarkers in NAFLD patients. | 2019 | Details |
| A10711 | 31226595 | J Hazard Mater | Chronic exposure to tetrabromodiphenyl ether (BDE-47) aggravates hepatic steatosis and liver fibrosis in diet-induced obese mice. | 2019 | Details |
| A10716 | 31225503 | Cell Stress | Hepatic stress associated with pathologies characterized by disturbed glucose production. | 2019 | Details |
| A10720 | 31222979 | J Cell Mol Med | Hepatic functional and pathological changes of type 1 diabetic mice in growing and maturation time. | 2019 | Details |
| A10736 | 31215672 | Hepatology | Sestrin 3 Protects Against Diet-Induced Nonalcoholic Steatohepatitis in Mice Through Suppression of Transforming Growth Factor β Signal Transduction. | 2019 | Details |
| A10742 | 31214115 | Front Endocrinol (Lausanne) | Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis. | 2019 | Details |
| A10767 | 31203627 | J Agric Food Chem | Polyphenol-Rich Loquat Fruit Extract Prevents Fructose-Induced Nonalcoholic Fatty Liver Disease by Modulating Glycometabolism, Lipometabolism, Oxidative Stress, Inflammation, Intestinal Barrier, and Gut Microbiota in Mice. | 2019 | Details |
| A10788 | 31191836 | Gastroenterol Hepatol Bed Bench | Pro-oxidant antioxidant balance in patients with non-alcoholic fatty liver disease. | 2019 | Details |
| A10792 | 31191323 | Front Pharmacol | Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A10793 | 31190566 | Arch Physiol Biochem | High-carbohydrate diet-induced metabolic disorders in Gerbillus tarabuli (a new model of non-alcoholic fatty-liver disease). Protective effects of 20-hydroxyecdysone. | 2019 | Details |
| A10819 | 31173696 | Appl Physiol Nutr Metab | Resveratrol protects against nonalcoholic fatty liver disease by improving lipid metabolism and redox homeostasis via the PPARα pathway. | 2019 | Details |
| A10820 | 31173506 | FASEB J | Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans. | 2019 | Details |
| A10823 | 31173180 | Int J Mol Med | Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin. | 2019 | Details |
| A10842 | 31162803 | Liver Int | Association between nut consumption and non-alcoholic fatty liver disease in adults. | 2019 | Details |
| A10844 | 31161464 | Neurochem Res | Food Selection of Cafeteria Diet Affects Memory Dysfunction Related to Obesity. | 2019 | Details |
| A10859 | 31153588 | Acta Histochem | A histomorphometric study on the hepatoprotective effects of a green rooibos extract in a diet-induced obese rat model. | 2019 | Details |
| A10860 | 31152791 | Free Radic Biol Med | Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease. | 2019 | Details |
| A10864 | 32953568 | J Tradit Complement Med | Calcium supplementation shows a hepatoprotective effect against high-fat diet by regulating oxidative-induced inflammatory response and lipogenesis activity in male rats. | 2019 | Details |
| A10866 | 31150631 | Chem Biol Interact | β-ionone inhibits nonalcoholic fatty liver disease and its association with hepatocarcinogenesis in male Wistar rats. | 2019 | Details |
| A10871 | 31147590 | Sci Rep | Effects of açai on oxidative stress, ER stress, and inflammation-related parameters in mice with high fat diet-fed induced NAFLD. | 2019 | Details |
| A10875 | 31145689 | Drug Metab Pers Ther | The effect of curcumin with piperine supplementation on pro-oxidant and antioxidant balance in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial. | 2019 | Details |