Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A50792 | 35264693 | Sci Rep | Clitorin ameliorates western diet-induced hepatic steatosis by regulating lipogenesis and fatty acid oxidation in vivo and in vitro. | 2022 | Details |
| A50807 | 35234696 | Chin Med J (Engl) | Therapeutic developments in metabolic dysfunction-associated fatty liver disease. | 2022 | Details |
| A50875 | 34675888 | Front Endocrinol (Lausanne) | Cardiovascular Endocrinology: Evolving Concepts and Updated Epidemiology of Relevant Diseases. | 2021 | Details |
| A50890 | 34271222 | Mol Metab | Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease. | 2021 | Details |
| A50892 | 34224877 | Clin Gastroenterol Hepatol | Liver Fibrosis in Asians With Metabolic Dysfunction-Associated Fatty Liver Disease. | 2021 | Details |
| A50943 | 35540668 | RSC Adv | Nifuroxazide ameliorates lipid and glucose metabolism in palmitate-induced HepG2 cells. | 2019 | Details |
| A50975 | 29298875 | Gut | Take me to the liver: adipose tissue macrophages coordinate hepatic neutrophil recruitment. | 2018 | Details |
| A50991 | 27817220 | Expert Rev Cardiovasc Ther | Ectopic fat: a target for cardiometabolic risk management. | 2016 | Details |
| A51020 | 24988092 | Minerva Med | Vitamin D and NAFLD: the need for interventional trials. | 2014 | Details |
| A51059 | 19015652 | Nat Clin Pract Gastroenterol Hepatol | What advice should be given to patients with NAFLD about the consumption of alcohol? | 2008 | Details |
| A51060 | 18980229 | Hepatology | Risk of severe liver disease in NAFLD with normal ALT levels: a pediatric report. | 2008 | Details |
| A51061 | 17911352 | Gut | Benefits of lifestyle modification in NAFLD. | 2007 | Details |
| A51063 | 17458261 | Nihon Rinsho | [Metabolic syndrome and NAFLD/NASH]. | 2006 | Details |
| A51069 | 16697746 | Gastroenterology | NAFLD, obesity, and bariatric surgery. | 2006 | Details |
| A51080 | 15685567 | Gastroenterology | Adiponectin--tipping the scales from NAFLD to NASH? | 2005 | Details |
| A51100 | 35766964 | J Med Food | Persimmon Water Extract Suppresses Hepatic Lipotoxicity by Regulating Lipid Metabolites. | 2022 | Details |
| A51105 | 35745205 | Nutrients | Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease. | 2022 | Details |
| A51109 | 35724630 | Obes Facts | The visceral fat area to hip circumstance ratio (VHR) as a predictor for insulin resistance in a Chinese population with type 2 diabetes. | 2022 | Details |
| A51110 | 35723657 | Child Obes | Probiotic Use in Children and Adolescents with Overweight or Obesity: A Scoping Review. | 2022 | Details |
| A51115 | 35678694 | Curr Issues Mol Biol | Lycopus lucidus Turcz Water Extract Ameliorates the Metabolic Disorder by Up-Regulated Major Urinary Protein Expression in High-Fat Diet-Induced Obesity. | 2022 | Details |
| A51121 | 35658903 | Mol Neurodegener | TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target. | 2022 | Details |
| A51125 | 35617705 | J Med Food | Partial Replacement of High-Fat Diet with Beef Tallow Attenuates Dyslipidemia and Endoplasmic Reticulum Stress in db/db Mice. | 2022 | Details |
| A51129 | 35600376 | Front Oncol | The Importance of Metabolic Syndrome Status for the Risk of Non-Viral Hepatocellular Carcinoma: A Nationwide Population-Based Study. | 2022 | Details |
| A51140 | 35512972 | Fertil Steril | Heart health in polycystic ovary syndrome: time to act on the data. | 2022 | Details |
| A51153 | 35458210 | Nutrients | The Dose-Response Effects of Consuming High Fructose Corn Syrup-Sweetened Beverages on Hepatic Lipid Content and Insulin Sensitivity in Young Adults. | 2022 | Details |
| A51161 | 35427802 | Clin Res Hepatol Gastroenterol | The mTORC1/AMPK pathway plays a role in the beneficial effects of semaglutide (GLP-1 receptor agonist) on the liver of obese mice. | 2022 | Details |
| A51162 | 35417107 | J Pediatr Endocrinol Metab | Successful treatment of severe hypertriglyceridemia with icosapent ethyl in a case of congenital generalized lipodystrophy type 4. | 2022 | Details |
| A51182 | 35323680 | Metabolites | Plasma Tsukushi Concentration Is Associated with High Levels of Insulin and FGF21 and Low Level of Total Cholesterol in a General Population without Medication. | 2022 | Details |
| A51186 | 35296424 | Biochim Biophys Acta Mol Cell Biol Lipids | Mechanisms of intestinal triacylglycerol synthesis. | 2022 | Details |
| A51227 | 10569299 | Am J Med | Association of nonalcoholic fatty liver disease with insulin resistance. | 1999 | Details |
| A51312 | 35700043 | J Clin Invest | Myeloid FoxO1 depletion attenuates hepatic inflammation and prevents nonalcoholic steatohepatitis. | 2022 | Details |
| A51317 | 35674880 | Clin Pharmacokinet | Effects of Hepatic Impairment on the Pharmacokinetics of the Dual GIP and GLP-1 Receptor Agonist Tirzepatide. | 2022 | Details |
| A51321 | 35625751 | Biomedicines | Influence of Type 2 Diabetes in the Association of PNPLA3 rs738409 and TM6SF2 rs58542926 Polymorphisms in NASH Advanced Liver Fibrosis. | 2022 | Details |
| A51330 | 35559132 | ACS Omega | Lipidomics Revealed Alteration of the Sphingolipid Metabolism in the Liver of Nonalcoholic Steatohepatitis Mice Treated with Scoparone. | 2022 | Details |
| A51332 | 35535116 | J Clin Exp Hepatol | An Approach to the Management of Diabetes Mellitus in Cirrhosis: A Primer for the Hepatologist. | 2021 | Details |
| A51357 | 35332108 | Aging (Albany NY) | Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment. | 2022 | Details |
| A51385 | 31024205 | J Clin Exp Hepatol | Hepatocellular Carcinoma: Etiology and Current and Future Drugs. | 2019 | Details |
| A51395 | 35830259 | FASEB J | Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH. | 2022 | Details |
| A51396 | 35830001 | Drugs | Tirzepatide: First Approval. | 2022 | Details |
| A51403 | 35780059 | J Clin Lipidol | Partial lipodystrophy, severe dyslipidaemia and insulin resistant diabetes as early signs of Werner syndrome. | 2022 | Details |
| A51412 | 35709720 | Semin Liver Dis | Non-Alcoholic Steatohepatitis Drug Development Pipeline: An Update. | 2022 | Details |
| A51413 | 35704699 | Am J Physiol Cell Physiol | The microRNA-29 family - role in metabolism and metabolic disease. | 2022 | Details |
| A51425 | 35592498 | Mol Ther Nucleic Acids | Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice. | 2022 | Details |
| A51426 | 35560370 | Hepatology | Lipocalin-2 Activates Hepatic stellate cells and Promotes Non-alcoholic Steatohepatitis in High-Fat Diet-Fed ob/ob mice. | 2022 | Details |
| A51449 | 35317186 | World J Hepatol | Glycogen hepatopathy in type-1 diabetes mellitus: A case report. | 2022 | Details |
| A51453 | 35285180 | FEBS J | HPS protects the liver against steatosis, cell death, inflammation, and fibrosis in mice with steatohepatitis. | 2022 | Details |
| A51497 | 35815420 | Hepatol Res | MAFLD Directly Related to Liver Fibrosis Independent of Insulin Resistance, Hyperlipidemia, and Alcohol Intake in Morbidly Obese Patients. | 2022 | Details |
| A51500 | 35794109 | Signal Transduct Target Ther | Trends in insulin resistance: insights into mechanisms and therapeutic strategy. | 2022 | Details |
| A51505 | 35764560 | Zhonghua Nei Ke Za Zhi | [Comparison of criteria for metabolically healthy overweight/obesity in Shanghai Changfeng study]. | 2022 | Details |
| A51506 | 35752830 | Lipids Health Dis | Comparison of the diagnostic value between triglyceride-glucose index and triglyceride to high-density lipoprotein cholesterol ratio in metabolic-associated fatty liver disease patients: a retrospective cross-sectional study. | 2022 | Details |
| A51507 | 35743314 | Int J Mol Sci | Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD. | 2022 | Details |
| A51508 | 35741222 | Diagnostics (Basel) | Urine Proteome in Distinguishing Hepatic Steatosis in Patients with Metabolic-Associated Fatty Liver Disease. | 2022 | Details |
| A51518 | 35691476 | Diabetes Res Clin Pract | Fatty liver indices and their association with glucose metabolism in pregnancy - An observational cohort study. | 2022 | Details |
| A51521 | 35655263 | Cardiovasc Diabetol | Impact of metabolic syndrome and metabolic dysfunction-associated fatty liver disease on cardiovascular risk by the presence or absence of type 2 diabetes and according to sex. | 2022 | Details |
| A51522 | 35631255 | Nutrients | Vitamin D Status Presents Different Relationships with Severity in Metabolic-Associated Fatty Liver Disease Patients with or without Hepatitis B Infection. | 2022 | Details |
| A51530 | 35532410 | J Clin Endocrinol Metab | Serum Thrombospondin-2 Levels Are Closely Associated With the Severity of Metabolic Syndrome and Metabolic Associated Fatty Liver Disease. | 2022 | Details |
| A51536 | 35491295 | Trends Endocrinol Metab | SGLT-2 inhibitors and GLP-1 receptor agonists in metabolic dysfunction-associated fatty liver disease. | 2022 | Details |
| A51540 | 35457118 | Int J Mol Sci | Emerging Evidence of Pathological Roles of Very-Low-Density Lipoprotein (VLDL). | 2022 | Details |
| A51542 | 35409324 | Int J Mol Sci | Meta-Inflammation and De Novo Lipogenesis Markers Are Involved in Metabolic Associated Fatty Liver Disease Progression in BTBR ob/ob Mice. | 2022 | Details |
| A51543 | 35401766 | J Exerc Sci Fit | Effects of one-year once-weekly high-intensity interval training on body adiposity and liver fat in adults with central obesity: Study protocol for a randomized controlled trial. | 2022 | Details |
| A51544 | 35394122 | Pediatr Obes | Development of a prediction protocol for the screening of metabolic associated fatty liver disease in children with overweight or obesity. | 2022 | Details |
| A51565 | 35081898 | Endocr Metab Immune Disord Drug Targets | Therapeutic effects and mechanism of liraglutide on rats with type 2 diabetes and metabolic-associated fatty liver disease. | 2022 | Details |
| A51572 | 35008356 | Cancers (Basel) | A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy. | 2021 | Details |
| A51580 | 34889064 | J Diabetes Investig | Circulating level of fatty acid-binding protein 4 is an independent predictor of metabolic dysfunction-associated fatty liver disease in middle-aged and elderly individuals. | 2022 | Details |
| A51585 | 34817168 | J Agric Food Chem | Estrogen Receptor α Regulates Metabolic-Associated Fatty Liver Disease by Targeting NLRP3-GSDMD Axis-Mediated Hepatocyte Pyroptosis. | 2021 | Details |
| A51590 | 34738404 | Zhongguo Zhong Yao Za Zhi | [Mechanism of Gynostemma pentaphyllum in treatment of metabolism associated fatty liver disease based on network pharmacology and molecular docking]. | 2021 | Details |
| A51594 | 34695608 | Mol Metab | Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability. | 2021 | Details |
| A51604 | 35729251 | Sci Rep | QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease. | 2022 | Details |
| A51611 | 35670755 | FASEB J | Normalization of maternal adiponectin in obese pregnant mice prevents programming of impaired glucose metabolism in adult offspring. | 2022 | Details |
| A51617 | 35618993 | J Gastrointest Surg | Sleeve Gastrectomy Improves High-Fat Diet-Associated Hepatic Steatosis Independent of the Glucagon-like-Petpide-1 Receptor in Rats. | 2022 | Details |
| A51619 | 35574038 | Front Endocrinol (Lausanne) | Role of Innate lymphoid Cells in Obesity and Insulin Resistance. | 2022 | Details |
| A51624 | 35508517 | Trends Endocrinol Metab | Diet- and microbiota-related metabolite, 5-aminovaleric acid betaine (5-AVAB), in health and disease. | 2022 | Details |
| A51627 | 35493783 | Anim Reprod | Rodent models in placental research. Implications for fetal origins of adult disease. | 2022 | Details |
| A51631 | 35483188 | Biomed Pharmacother | Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer's disease. | 2022 | Details |
| A51638 | 35421452 | Life Sci | Characteristics and molecular mechanisms through which SGLT2 inhibitors improve metabolic diseases: A mechanism review. | 2022 | Details |
| A51642 | 35325655 | Biochem Biophys Res Commun | 3-Hydroxyacyl-CoA dehydratase 2 deficiency confers resistance to diet-induced obesity and glucose intolerance. | 2022 | Details |
| A51645 | 35295579 | Front Physiol | Antisense Oligonucleotide Technologies to Combat Obesity and Fatty Liver Disease. | 2022 | Details |
| A51651 | 35268696 | Molecules | A Comprehensive Review on Therapeutic Perspectives of Phytosterols in Insulin Resistance: A Mechanistic Approach. | 2022 | Details |
| A51652 | 35252948 | J Mass Spectrom Adv Clin Lab | Use of ultra high performance liquid chromatography with high resolution mass spectrometry to analyze urinary metabolome alterations following acute kidney injury in post-cardiac surgery patients. | 2022 | Details |
| A51656 | 35212667 | AIDS | Higher epicardial fat in older adults living with HIV with viral suppression and relationship with liver steatosis, coronary calcium and cardiometabolic risks. | 2022 | Details |
| A51659 | 35187139 | Front Vet Sci | Differentiation of Subclinical Ketosis and Liver Function Test Indices in Adipose Tissues Associated With Hyperketonemia in Postpartum Dairy Cattle. | 2022 | Details |
| A51661 | 35173282 | Int J Obes (Lond) | Association of plasma kynurenine pathway metabolite concentrations with metabolic health risk in prepubertal Asian children. | 2022 | Details |
| A51664 | 35115945 | Front Pharmacol | Anti-Inflammatory and Pro-Autophagy Effects of the Cannabinoid Receptor CB2R: Possibility of Modulation in Type 1 Diabetes. | 2022 | Details |
| A51665 | 35097227 | Emerg Contam | Latent, sex-specific metabolic health effects in CD-1 mouse offspring exposed to PFOA or HFPO-DA (GenX) during gestation. | 2021 | Details |
| A51669 | 35070060 | World J Diabetes | Gut microbiota-derived metabolites are novel targets for improving insulin resistance. | 2022 | Details |
| A51674 | 35040267 | Physiol Rep | Macrophage activation marker sCD163 is associated with liver injury and hepatic insulin resistance in obese patients before and after Roux-en-Y gastric bypass. | 2022 | Details |
| A51679 | 34998544 | J Dairy Sci | Temporal profiles describing markers of inflammation and metabolism during the transition period of pasture-based, seasonal-calving dairy cows. | 2022 | Details |
| A51681 | 34959746 | Nutrients | Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics. | 2021 | Details |
| A51694 | 34847289 | FEBS J | Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk. | 2021 | Details |
| A51696 | 34836963 | Nat Commun | CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease. | 2021 | Details |
| A51705 | 34774157 | Lancet Gastroenterol Hepatol | Metabolic dysfunction-associated fatty liver disease and insulin resistance in type 1 diabetes. | 2021 | Details |
| A51706 | 34758301 | Cell Rep | The hepatic compensatory response to elevated systemic sulfide promotes diabetes. | 2021 | Details |
| A51708 | 34722722 | Visc Med | Obesity and Gallstones. | 2021 | Details |
| A51710 | 34722187 | J Clin Transl Hepatol | Alcohol and Metabolic-associated Fatty Liver Disease. | 2021 | Details |
| A51721 | 34603196 | Front Endocrinol (Lausanne) | Serum Afamin a Novel Marker of Increased Hepatic Lipid Content. | 2021 | Details |
| A51725 | 34578953 | Nutrients | Maternal DHA Supplementation during Pregnancy and Lactation in the Rat Protects the Offspring against High-Calorie Diet-Induced Hepatic Steatosis. | 2021 | Details |
| A51727 | 34563954 | Biomed Pharmacother | Transcriptome analysis to reveal the mechanism of the effect of Echinops latifolius polysaccharide B on palmitate-induced insulin-resistant. | 2021 | Details |
| A51733 | 34502170 | Int J Mol Sci | Pleiotrophin Deficiency Induces Browning of Periovarian Adipose Tissue and Protects against High-Fat Diet-Induced Hepatic Steatosis. | 2021 | Details |
| A51735 | 34471717 | Heliyon | Adiponectin gene polymorphisms associated with diabetes mellitus: A descriptive review. | 2021 | Details |
| A51762 | 34302121 | Int J Obes (Lond) | Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae. | 2021 | Details |