Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A48085 | 24585431 | Hepatology | Prevalence and natural history of histologically proven chronic liver disease in a longitudinal cohort of patients with type 1 diabetes. | 2014 | Details |
| A48086 | 24524100 | Drugs Today (Barc) | The Liver Meeting 2013: a report from the 64th meeting of the American Association for the Study of the Liver (November 1-5, 2013 - Washington, D.C., USA). | 2013 | Details |
| A48088 | 24445078 | J Nutr Biochem | Sesame oil attenuates nutritional fibrosing steatohepatitis by modulating matrix metalloproteinases-2, 9 and PPAR-γ. | 2013 | Details |
| A48092 | 24204981 | PLoS One | Aliskiren attenuates steatohepatitis and increases turnover of hepatic fat in mice fed with a methionine and choline deficient diet. | 2013 | Details |
| A48100 | 23630312 | Radiology | Liver fibrosis: noninvasive assessment with acoustic radiation force impulse elastography--comparison with FibroScan M and XL probes and FibroTest in patients with chronic liver disease. | 2013 | Details |
| A48101 | 23565350 | Curr Pathobiol Rep | MicroRNAs in Liver Health and Disease. | 2013 | Details |
| A48106 | 23323257 | Clin Mol Hepatol | Severe steatohepatitis with hepatic decompensation resulting from malnutrition after pancreaticoduodenectomy. | 2012 | Details |
| A48111 | 23172830 | Liver Transpl | Influence of age and gender before and after liver transplantation. | 2013 | Details |
| A48117 | 22699820 | Cell Mol Life Sci | Peroxisome proliferator-activated receptor-γ as a therapeutic target for hepatic fibrosis: from bench to bedside. | 2012 | Details |
| A48118 | 24159567 | Liver Cancer | Epidemiology and surveillance of hepatocellular carcinoma. | 2012 | Details |
| A48120 | 22556147 | Am J Physiol Gastrointest Liver Physiol | Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet. | 2012 | Details |
| A48121 | 22556142 | Am J Physiol Gastrointest Liver Physiol | Steatohepatitis in laboratory opossums exhibiting a high lipemic response to dietary cholesterol and fat. | 2012 | Details |
| A48125 | 22498821 | Am J Surg Pathol | Reticulin loss in benign fatty liver: an important diagnostic pitfall when considering a diagnosis of hepatocellular carcinoma. | 2012 | Details |
| A48127 | 22333480 | J Pharmacol Sci | Multiple mechanisms for the action of chymase inhibitors. | 2012 | Details |
| A48130 | 22239000 | Pol Merkur Lekarski | [Cytokeratin 18 as an indicator of the activity of liver disease]. | 2011 | Details |
| A48131 | 22150762 | Inflamm Allergy Drug Targets | Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis. | 2011 | Details |
| A48134 | 21979752 | Mol Med | p38 mitogen-activated protein kinase and liver X receptor-α mediate the leptin effect on sterol regulatory element binding protein-1c expression in hepatic stellate cells. | 2012 | Details |
| A48137 | 21894007 | Dig Dis | Modulation of liver fibrosis by adipokines. | 2011 | Details |
| A48138 | 21830829 | J Proteome Res | A comprehensive untargeted metabonomic analysis of human steatotic liver tissue by RP and HILIC chromatography coupled to mass spectrometry reveals important metabolic alterations. | 2011 | Details |
| A48147 | 21399975 | Abdom Imaging | Hepatocellular nodules in liver cirrhosis: MR evaluation. | 2011 | Details |
| A48148 | 21351243 | Liver Transpl | Metabolic syndrome and nonalcoholic steatohepatitis recurrence after liver transplantation in children. | 2011 | Details |
| A48155 | 21128703 | Antioxid Redox Signal | Mitochondria and redox signaling in steatohepatitis. | 2011 | Details |
| A48164 | 20861239 | Endocrinology | Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity. | 2010 | Details |
| A48167 | 20844968 | Ann Surg Oncol | Sinusoidal obstruction syndrome impairs long-term outcome of colorectal liver metastases treated with resection after neoadjuvant chemotherapy. | 2010 | Details |
| A48169 | 20814892 | Hepatology | Smoking is associated with histological severity in nonalcoholic steatohepatitis. | 2010 | Details |
| A48170 | 20812358 | Hepatology | Clinical syndromes and consequences of antiretroviral-related hepatotoxicity. | 2010 | Details |
| A48172 | 20697377 | Lab Invest | Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet. | 2010 | Details |
| A48176 | 20660066 | Endocrinology | Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids. | 2010 | Details |
| A48178 | 20651240 | Am J Pathol | Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis. | 2010 | Details |
| A48180 | 20630622 | Gastroenterol Hepatol | [Reversibility of hepatitis B virus-induced liver cirrhosis after prolonged antiviral therapy]. | 2010 | Details |
| A48188 | 20223120 | Zhonghua Yi Xue Za Zhi | [Mechanism of hepatocyte regeneration inhibition in rats with liver fibrosis induced by lipogenic methionine-choline- deficient diet]. | 2009 | Details |
| A48189 | 20162727 | Hepatology | CXC chemokine ligand 4 (Cxcl4) is a platelet-derived mediator of experimental liver fibrosis. | 2010 | Details |
| A48193 | 20093230 | Am J Clin Pathol | Bile ductular cells undergoing cellular senescence increase in chronic liver diseases along with fibrous progression. | 2010 | Details |
| A48196 | 20019598 | Blood Coagul Fibrinolysis | Natural anticoagulants can be useful predictors of severity in chronic liver disease. | 2010 | Details |
| A48203 | 19901911 | Lab Invest | Curcumin limits the fibrogenic evolution of experimental steatohepatitis. | 2009 | Details |
| A48205 | 19808779 | Endocrinology | Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1. | 2009 | Details |
| A48211 | 19587308 | Radiology | Early detection of steatohepatitis in fatty rat liver by using MR elastography. | 2009 | Details |
| A48217 | 19478678 | Eur J Gastroenterol Hepatol | Relationships between fibrosis amounts assessed by morphometry and liver stiffness measurements in chronic hepatitis or steatohepatitis. | 2009 | Details |
| A48223 | 19346786 | Korean J Hepatol | [The value of serum retinol-binding protein 4 levels for determining disease severity in patients with chronic liver disease]. | 2009 | Details |
| A48225 | 19307461 | Exp Biol Med (Maywood) | Improvement in dissolution of liver fibrosis in an animal model by tetrathiomolybdate. | 2009 | Details |
| A48247 | 18807886 | No To Hattatsu | [Immunohistochemical analysis of hepatic steatosis in autopsy cases of severe motor and intellectual disabilities]. | 2008 | Details |
| A48249 | 18715620 | Hum Pathol | Apoptosis markers in liver biopsy of nonalcoholic steatohepatitis in pediatric patients. | 2008 | Details |
| A48254 | 18408454 | Curr Opin Gastroenterol | Hepatobiliary pathology. | 2008 | Details |
| A48267 | 18032466 | Am J Physiol Regul Integr Comp Physiol | Attenuation of acute and chronic liver injury in rats by iron-deficient diet. | 2007 | Details |
| A48285 | 17369113 | Dig Liver Dis | Essential hypertension and chronic viral hepatitis. | 2007 | Details |
| A48295 | 17135584 | N Engl J Med | A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. | 2006 | Details |
| A48302 | 17023554 | Am J Physiol Gastrointest Liver Physiol | Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis. | 2006 | Details |
| A48309 | 16958000 | Dig Dis Sci | Leptin in the field of hepatic fibrosis: a pivotal or an incidental player? | 2006 | Details |
| A48318 | 16803426 | Pharmacotherapy | Thalidomide-induced severe hepatotoxicity. | 2006 | Details |
| A48327 | 16407588 | Am J Physiol Gastrointest Liver Physiol | Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis. | 2006 | Details |
| A48328 | 16396370 | Rev Med Suisse | [Nonalcoholic fatty liver: does it have to be biopsed?]. | 2005 | Details |
| A48329 | 16390234 | Arch Pathol Lab Med | Diabetic hepatosclerosis: diabetic microangiopathy of the liver. | 2006 | Details |
| A48330 | 16378280 | Turk J Gastroenterol | Obesity and related parameters of non-alcoholic steatohepatitis. | 2002 | Details |
| A48332 | 16283935 | BMC Gastroenterol | Measurement of the total antioxidant response using a novel automated method in subjects with nonalcoholic steatohepatitis. | 2005 | Details |
| A48333 | 16265071 | Nat Clin Pract Gastroenterol Hepatol | Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications. | 2004 | Details |
| A48340 | 16162162 | Liver Int | High glucose stimulates hepatic stellate cells to proliferate and to produce collagen through free radical production and activation of mitogen-activated protein kinase. | 2005 | Details |
| A48347 | 15787813 | Br J Dermatol | Monitoring patients on methotrexate: hepatic fibrosis not seen in patients with normal serum assays of aminoterminal peptide of type III procollagen. | 2005 | Details |
| A48348 | 15738389 | Proc Natl Acad Sci U S A | Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia. | 2005 | Details |
| A48355 | 15567150 | Biochem Biophys Res Commun | Deficiency of inducible nitric oxide synthase exacerbates hepatic fibrosis in mice fed high-fat diet. | 2005 | Details |
| A48356 | 15561241 | Transplant Proc | Revealing the cause of cryptogenic cirrhosis by posttransplant liver biopsy. | 2004 | Details |
| A48372 | 14627331 | Dig Dis Sci | Nonalcoholic steatohepatitis--a long-term follow-up study: comparison with alcoholic hepatitis in ambulatory and hospitalized patients. | 2003 | Details |
| A48373 | 14586875 | Liver Transpl | Delayed onset of severe hepatitis C-related liver damage following liver transplantation: a matter of concern? | 2003 | Details |
| A48377 | 14506613 | Metabolism | Aldehyde dehydrogenase 2 and beta3-adrenergic receptor gene polymorphisms: their association with elevated liver enzymes and metabolic syndrome. | 2003 | Details |
| A48396 | 12568185 | Obes Surg | Liver damage in obese patients. | 2002 | Details |
| A48405 | 12358273 | Am J Gastroenterol | Obese children with steatohepatitis can develop cirrhosis in childhood. | 2002 | Details |
| A48407 | 12122863 | Clin Liver Dis | Alcoholic and nonalcoholic steatohepatitis. | 2002 | Details |
| A48419 | 11832443 | Gastroenterology | Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis. | 2002 | Details |
| A48427 | 11391539 | Hepatology | Intrahepatic hepatitis C viral RNA status of serum polymerase chain reaction-negative individuals with histological changes on liver biopsy. | 2001 | Details |
| A48428 | 11269008 | Hepatogastroenterology | Hepatic stellate cell activation occurs in nonalcoholic steatohepatitis. | 2001 | Details |
| A48433 | 11110619 | Can J Gastroenterol | Iron and liver diseases. | 2000 | Details |
| A48434 | 11097478 | J Hepatol | Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity. | 2000 | Details |
| A48437 | 10990076 | Diabetologia | Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with type II diabetes. | 2000 | Details |
| A48438 | 10980924 | Curr Gastroenterol Rep | Role of HFE gene mutations in liver diseases other than hereditary hemochromatosis. | 2000 | Details |
| A48444 | 10630439 | J Pediatr Gastroenterol Nutr | Nonalcoholic steatohepatitis in children. | 2000 | Details |
| A48446 | 10553793 | JAMA | Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. | 1999 | Details |
| A48450 | 10348825 | Gastroenterology | Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. | 1999 | Details |
| A48455 | 9731566 | Hepatology | Expression of cyclin-dependent kinase inhibitor p21 in human liver. | 1998 | Details |
| A48460 | 9412973 | J Clin Gastroenterol | Nonalcoholic steatohepatitis masquerading as autoimmune hepatitis. | 1997 | Details |
| A48470 | 8565753 | Dig Dis Sci | Nonalcoholic steatohepatitis. Clinicopathological comparison with alcoholic hepatitis in ambulatory and hospitalized patients. | 1996 | Details |
| A48471 | 7489979 | Hepatology | The natural history of nonalcoholic fatty liver: a follow-up study. | 1995 | Details |
| A48480 | 7523217 | Gastroenterology | Nonalcoholic steatohepatitis: an expanded clinical entity. | 1994 | Details |
| A48481 | 8234924 | Recent Dev Alcohol | Recent developments in alcoholism:the liver. | 1993 | Details |
| A48482 | 2227807 | Hepatology | Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. | 1990 | Details |
| A48486 | 3605026 | Am J Gastroenterol | Comparison between nonalcoholic steatohepatitis and alcoholic hepatitis. | 1987 | Details |
| A48495 | 7382552 | Mayo Clin Proc | Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. | 1980 | Details |
| A48496 | 6447063 | Endoscopy | Comparative studies of laparoscopy, histology and gray-scale echotomography in diffuse diseases of the liver. | 1980 | Details |
| A48502 | 35255183 | Liver Transpl | Prediction of long-term morbidity and mortality after liver transplantation using two-dimensional shear wave elastography as compared to liver biopsy. | 2022 | Details |
| A48503 | 35232008 | Clin Mol Hepatol | The emerging roles of extracellular vesicles as intercellular messengers in liver physiology and pathology. | 2022 | Details |
| A48512 | 35075250 | Cell Death Differ | The multifaceted role of ferroptosis in liver disease. | 2022 | Details |
| A48514 | 35048542 | Liver Int | Integrins as a drug target in liver fibrosis. | 2022 | Details |
| A48523 | 34904513 | Scand J Gastroenterol | The relationship between portal hypertension and portal hypertensive gastropathy. | 2021 | Details |
| A48527 | 34727968 | BMC Res Notes | Placental extract suppresses the formation of fibrotic deposits by tumor necrosis factor alpha and transforming growth factor beta-induced epithelial-mesenchymal transition in ARPE-19 cells. | 2021 | Details |
| A48531 | 34640373 | J Clin Med | FibroScan-AST Score Predicts 30-Day Mortality or Need for Mechanical Ventilation among Patients Hospitalized with COVID-19. | 2021 | Details |
| A48543 | 34364916 | J Hepatol | Dark and bright side of targeting fibroblast growth factor receptor 4 in the liver. | 2021 | Details |
| A48544 | 34364773 | Nutr Metab Cardiovasc Dis | Hepatic fibrosis of any origin in a large population of type 2 diabetes patients. | 2021 | Details |
| A48552 | 34228359 | J Pathol | Periostin deficiency reduces diethylnitrosamine-induced liver cancer in mice by decreasing hepatic stellate cell activation and cancer cell proliferation. | 2021 | Details |
| A48555 | 34192073 | SA J Radiol | Preliminary experience with 3T magnetic resonance elastography imaging of the liver. | 2021 | Details |
| A48560 | 34093007 | Drug Des Devel Ther | Incidence and Risk Factors of Hepatic Fibrosis in Psoriatic Patients Receiving Methotrexate with Concomitant Acitretin Therapy and Methotrexate Monotherapy. | 2021 | Details |
| A48563 | 34066850 | Microorganisms | Human Gut Microbiome and Liver Diseases: From Correlation to Causation. | 2021 | Details |
| A48567 | 33917706 | Pharmaceutics | Effect of Curcumin Nanoemulsions Stabilized with MAG and DAG-MCFAs in a Fructose-Induced Hepatic Steatosis Rat Model. | 2021 | Details |