Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A50020 | 35562658 | BMC Gastroenterol | Distribution of FIB-4 index in the general population: analysis of 75,666 residents who underwent health checkups. | 2022 | Details |
| A50021 | 35561146 | Hepatology | Metabolic reprogramming of the intestinal microbiome with functional bile acid changes underlie the development of NAFLD. | 2022 | Details |
| A50022 | 35560825 | Hepatol Commun | Mid-upper arm circumference is associated with liver steatosis and fibrosis in patients with metabolic-associated fatty liver disease: A population based observational study. | 2022 | Details |
| A50023 | 35560106 | Hepatology | Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children. | 2022 | Details |
| A50025 | 35559337 | Front Med (Lausanne) | The Apparent Asymmetrical Relationship Between Small Bowel Bacterial Overgrowth, Endotoxemia, and Liver Steatosis and Fibrosis in Cirrhotic and Non-Cirrhotic Patients: A Single-Center Pilot Study. | 2022 | Details |
| A50029 | 35558748 | Front Nutr | Association Between Skeletal Muscle Mass and Severity of Steatosis and Fibrosis in Non-alcoholic Fatty Liver Disease. | 2022 | Details |
| A50030 | 35558366 | Front Pediatr | Non-Invasive Diagnostic Test for Advanced Fibrosis in Adolescents With Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A50035 | 35553006 | Hepatol Int | Automated fibrosis phenotyping of liver tissue from non-tumor lesions of patients with and without hepatocellular carcinoma after liver transplantation for non-alcoholic fatty liver disease. | 2022 | Details |
| A50040 | 35550529 | Biomed Pharmacother | The anti-inflammatory effect of Pien Tze Huang in non-alcoholic fatty liver disease. | 2022 | Details |
| A50048 | 35546386 | J Physiol Biochem | The serum uric acid/creatinine ratio is associated with nonalcoholic fatty liver disease in the general population. | 2022 | Details |
| A50057 | 35543116 | Hepatol Res | Comparison of thrombocytopenia between patients with non-alcoholic fatty liver disease and those with hepatitis C virus-related chronic liver disease. | 2022 | Details |
| A50059 | 35540106 | JHEP Rep | Molecular characterization of chronic liver disease dynamics: From liver fibrosis to acute-on-chronic liver failure. | 2022 | Details |
| A50064 | 35537911 | Rev Gastroenterol Mex (Engl Ed) | Prevalence and clinical-epidemiologic characteristics of a Mexican population with metabolic (dysfunction) associated fatty liver disease: An open population study. | 2022 | Details |
| A50073 | 35535092 | J Clin Exp Hepatol | Diabetes Mellitus Increases the Risk of Significant Hepatic Fibrosis in Patients With Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A50075 | 35535086 | J Clin Exp Hepatol | Prevalence and Predictors of Nonalcoholic Fatty Liver Disease in Family Members of Patients With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A50076 | 35535068 | J Clin Exp Hepatol | FibroScan-AST (FAST) Score for Nonalcoholic Steatohepatitis - Validation in an Indian Cohort. | 2021 | Details |
| A50078 | 35535064 | J Clin Exp Hepatol | Characterization and Pharmacological Validation of a Preclinical Model of NASH in Göttingen Minipigs. | 2021 | Details |
| A50080 | 35534573 | Nat Rev Endocrinol | Macrophage functional diversity in NAFLD - more than inflammation. | 2022 | Details |
| A50081 | 35534202 | J Clin Pathol | Postmortem survey of haemoglobin A1c, non-alcoholic steatohepatitis and liver fibrosis within a general population. | 2022 | Details |
| A50087 | 35532850 | Hormones (Athens) | Menopausal hormone therapy in women with dyslipidemia and nonalcoholic fatty liver disease. | 2022 | Details |
| A50093 | 35530830 | Cureus | Hepatic Glycogenosis: An Underdiagnosed Entity? | 2022 | Details |
| A50095 | 35528989 | J Clin Transl Hepatol | Glutaminolysis-ammonia-urea Cycle Axis, Non-alcoholic Fatty Liver Disease Progression and Development of Novel Therapies. | 2022 | Details |
| A50098 | 35528974 | J Clin Transl Hepatol | Metabolic Dysfunction-associated Fatty Liver Disease is Associated with Greater Impairment of Lung Function than Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A50099 | 35528971 | J Clin Transl Hepatol | Metabolic-associated Fatty Liver Disease (MAFLD): A Multi-systemic Disease Beyond the Liver. | 2021 | Details |
| A50100 | 35528969 | J Clin Transl Hepatol | Redefinition of Fatty Liver Disease from NAFLD to MAFLD through the Lens of Drug Development and Regulatory Science. | 2021 | Details |
| A50102 | 35528151 | Acta Clin Croat | CROATIAN GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF NONALCOHOLIC FATTY LIVER DISEASE. | 2021 | Details |
| A50103 | 35527706 | Hepatol Commun | Nonalcoholic fatty liver disease prevalence and severity in Asian Americans from the national health and nutrition examination surveys 2017-2018. | 2022 | Details |
| A50104 | 35527326 | Eat Weight Disord | Concordance between indirect fibrosis and steatosis indices and their predictors in subjects with overweight/obesity. | 2022 | Details |
| A50106 | 35525796 | Pathology | Prevalence and clinical significance of portal inflammation, portal plasma cells, interface hepatitis and biliary injury in liver biopsies from patients with non-alcoholic steatohepatitis. | 2022 | Details |
| A50109 | 35523460 | BMJ Open Gastroenterol | Prevalence of frailty in patients with non-cirrhotic non-alcoholic fatty liver disease. | 2022 | Details |
| A50111 | 35521691 | Bioengineered | The macrophage-associated microRNA-4715-3p / Gasdermin D axis potentially indicates fibrosis progression in nonalcoholic fatty liver disease: evidence from transcriptome and biological data. | 2022 | Details |
| A50112 | 35521658 | Antioxid Redox Signal | RGS7-ATF3-Tip60 Complex Promotes Hepatic Steatosis and Fibrosis by Directly Inducing TNFα. | 2022 | Details |
| A50113 | 35518541 | Cureus | Nonalcoholic Fatty Liver Disease: Could It Be the Next Medical Tsunami? | 2022 | Details |
| A50114 | 35518363 | Cureus | Whether Screening for Non-alcoholic Fatty Liver Disease in Patients With Psoriasis Is Necessary: A Pilot Quality Improvement Project. | 2022 | Details |
| A50119 | 35514152 | Hepatology | NAFLD improves risk prediction of type 2 diabetes: with effect modification by sex and menopausal status. | 2022 | Details |
| A50120 | 35513902 | J Hepatol | NAFLD/NASH. | 2022 | Details |
| A50121 | 35513235 | Clin Gastroenterol Hepatol | Mortality Outcomes by Fibrosis Stage in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2022 | Details |
| A50123 | 35512974 | Fertil Steril | Nonalcoholic fatty liver disease and obstructive sleep apnea in women with polycystic ovary syndrome. | 2022 | Details |
| A50129 | 35509420 | Therap Adv Gastroenterol | Prognostic utility of magnetic resonance elastography and MEFIB index in predicting liver-related outcomes and mortality in individuals at risk of and with nonalcoholic fatty liver disease. | 2022 | Details |
| A50131 | 35508720 | Acta Pharmacol Sin | Hepatocyte-derived VEGFA accelerates the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via activating hepatic stellate cells. | 2022 | Details |
| A50136 | 35507280 | Curr Atheroscler Rep | Comprehensive Review and Updates on Holistic Approach Towards Non-Alcoholic Fatty Liver Disease Management with Cardiovascular Disease. | 2022 | Details |
| A50138 | 35507246 | Front Med | New definition of metabolic dysfunction-associated fatty liver disease with elevated brachial-ankle pulse wave velocity and albuminuria: a prospective cohort study. | 2022 | Details |
| A50144 | 35503803 | Hepatol Commun | Skeletal muscle mass to visceral fat area ratio as a predictor of NAFLD in lean and overweight men and women with effect modification by sex. | 2022 | Details |
| A50148 | 35503180 | Adv Exp Med Biol | Manifold Roles of Ceramide Metabolism in Non-Alcoholic Fatty Liver Disease and Liver Cancer. | 2022 | Details |
| A50153 | 35501557 | Curr Obes Rep | Anti-obesity Medications for the Management of Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A50159 | 35500155 | Acta Physiol (Oxf) | Microbial DNA enrichment promotes liver steatosis and fibrosis in the course of non-alcoholic steatohepatitis. | 2022 | Details |
| A50165 | 35494925 | Cureus | Relationship Between Greyscale Ultrasound Grading of Hepatic Steatosis and Attenuation Imaging. | 2022 | Details |
| A50168 | 35492369 | Front Med (Lausanne) | Comparison of FibroScan-Aspartate Aminotransferase (FAST) Score and Other Non-invasive Surrogates in Predicting High-Risk Non-alcoholic Steatohepatitis Criteria. | 2022 | Details |
| A50182 | 35486350 | Ir J Med Sci | Reduced and more appropriate referrals of patients with type 2 diabetes using liver stiffness measurement compared to FIB-4. | 2022 | Details |
| A50184 | 35485970 | Eur J Neurol | Liver Fibrosis-4 index indicates atrial fibrillation in acute ischemic stroke. | 2022 | Details |
| A50186 | 35485357 | J Physiol Pharmacol | Very low-volume interval training improves nonalcoholic fatty liver disease fibrosis score and cardiometabolic health in adults with obesity and metabolic syndrome. | 2022 | Details |
| A50187 | 35485207 | Hepatol Commun | A new detection system for serum fragmented cytokeratin 18 as a biomarker reflecting histologic activities of human nonalcoholic steatohepatitis. | 2022 | Details |
| A50190 | 35484644 | Clin Mol Hepatol | Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in NAFLD mouse models using modified basket trial. | 2022 | Details |
| A50195 | 35483092 | J Comput Assist Tomogr | Diagnostic Feasibility of Magnetic Resonance Elastography Radiomics Analysis for the Assessment of Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A50196 | 35481312 | Cureus | Hepatocellular Carcinoma With Right Atrium Metastases. | 2022 | Details |
| A50199 | 35479585 | Ann Gastroenterol | The association of weight gain with nonalcoholic fatty liver disease and fibrosis detected by FibroScan in the United States. | 2022 | Details |
| A50201 | 35478356 | Hepatol Commun | Serum Mac-2 binding protein level predicts the development of liver-related events and colorectal cancer in patients with NAFLD. | 2022 | Details |
| A50202 | 35477908 | Hepatology | The steatosis-associated fibrosis estimator (SAFE) score: A tool to detect low-risk NAFLD in primary care. | 2022 | Details |
| A50205 | 35476028 | J Mol Med (Berl) | Receptor-interacting protein kinase-1 ablation in liver parenchymal cells promotes liver fibrosis in murine NASH without affecting other symptoms. | 2022 | Details |
| A50208 | 35475465 | Histol Histopathol | Characterization of diet based nonalcoholic fatty liver disease/nonalcoholic steatohepatitis in rodent models: Histological and biochemical outcomes. | 2022 | Details |
| A50210 | 35474232 | Hepatology | Association between birth weight, preterm birth, and nonalcoholic fatty liver disease in a community-based cohort. | 2022 | Details |
| A50212 | 35472433 | J Nutr Biochem | Chlorogenic acid alleviated liver fibrosis in methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice and its mechanism. | 2022 | Details |
| A50216 | 35469222 | Comput Math Methods Med | Screening Potential Drugs for the Development of NAFLD Based on Drug Perturbation Gene Set. | 2022 | Details |
| A50221 | 35467297 | Clin Drug Investig | General Overview About the Current Management of Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A50222 | 35467042 | J Gastroenterol Hepatol | Gamma-glutamyl transpeptidase dynamics as a biomarker for advanced fibrosis in non-alcoholic fatty liver disease. | 2022 | Details |
| A50226 | 35465068 | Gastroenterol Hepatol (N Y) | Nonalcoholic Fatty Liver Disease in Children. | 2021 | Details |
| A50227 | 35464866 | Front Genet | Genetic Variants of Glycogen Metabolism Genes Were Associated With Liver PDFF Without Increasing NAFLD Risk. | 2022 | Details |
| A50232 | 35463006 | Front Med (Lausanne) | Liver Fibrosis Scores and Clinical Outcomes in Patients With COVID-19. | 2022 | Details |
| A50235 | 35462487 | Zhonghua Gan Zang Bing Za Zhi | [Exploring the effects of entecavir treatment on the degree of liver fibrosis in patients with non-alcoholic fatty liver combined with chronic hepatitis B in Tibet region]. | 2022 | Details |
| A50241 | 35461369 | Sci Rep | Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis. | 2022 | Details |
| A50243 | 35460926 | Biomed J | Prognosis of Chronic Kidney Disease in Patients with Non-Alcoholic Fatty Liver Disease: a Northeastern Taiwan Community Medicine Research Cohort. | 2022 | Details |
| A50254 | 35453964 | Diagnostics (Basel) | Association of Non-Alcoholic Fatty Liver Disease and Hepatic Fibrosis with Epicardial Adipose Tissue Volume and Atrial Deformation Mechanics in a Large Asian Population Free from Clinical Heart Failure. | 2022 | Details |
| A50255 | 35453849 | Diagnostics (Basel) | Clinical and Laboratory Characteristics of Normal Weight and Obese Individuals with Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A50256 | 35453652 | Biomedicines | Potential Therapeutic Targets and Promising Agents for Combating NAFLD. | 2022 | Details |
| A50257 | 35452693 | J Hepatol | Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis. | 2022 | Details |
| A50259 | 35451807 | Curr Med Sci | Efficacy of Sitagliptin on Nonalcoholic Fatty Liver Disease in High-fat-diet-fed Diabetic Mice. | 2022 | Details |
| A50261 | 35450873 | BMJ Case Rep | Case of GPD1 deficiency causing hypertriglyceridaemia and non-alcoholic steatohepatitis. | 2022 | Details |
| A50267 | 35449229 | Sci Rep | Transient elastography and serum markers of liver fibrosis associate with epicardial adipose tissue and coronary artery calcium in NAFLD. | 2022 | Details |
| A50274 | 35447548 | Biomed Pharmacother | Downregulation of hepatic fat accumulation, inflammation and fibrosis by nerolidol in purpose built western-diet-induced multiple-hit pathogenesis of NASH animal model. | 2022 | Details |
| A50277 | 35447114 | J Biol Chem | Leukemia inhibitory factor protects against liver steatosis in nonalcoholic fatty liver disease patients and obese mice. | 2022 | Details |
| A50279 | 35444966 | Front Pediatr | Stratification by Non-invasive Biomarkers of Non-alcoholic Fatty Liver Disease in Children. | 2022 | Details |
| A50284 | 35443531 | J Assoc Physicians India | Clinical Characteristics and Metabolic Profiles of Non-Alcoholic Fatty Liver Disease (NAFLD) in Lean Patients and Their Comparison with Obese and Overweight NAFLD. | 2022 | Details |
| A50285 | 35443488 | J Assoc Physicians India | Comparison of Novel Fibrosis Index (NFI) with Aspartate aminotransferase to platelet ratio index (APRI) in Type II Diabetes mellitus patients with Non alcoholic fatty liver disease and fibrosis (NAFLD). | 2022 | Details |
| A50287 | 35443467 | J Assoc Physicians India | Assessment of liver fibrosis using non-invasive screening tools in individuals with diabetes mellitus and metabolic syndrome. | 2022 | Details |
| A50290 | 35442594 | Int J Med Mushrooms | Meal Ingestion of Ceraceomyces tessulatus Strain BDM-X (Agaricomycetes) Protects against Nonalcoholic Steatohepatitis in Mice. | 2022 | Details |
| A50293 | 35442320 | Arq Gastroenterol | SHOULD ROUTINE LIVER BIOPSY BE CONSIDERED IN BARIATRIC SURGICAL PRACTICE? AN ANALYSIS OF THE LIMITATIONS OF NON-INVASIVE NAFLD MARKERS. | 2022 | Details |
| A50297 | 35440282 | Int J Circumpolar Health | Non-alcoholic fatty liver disease in patients with type 2 diabetes in Greenland: a register-based cross-sectional study. | 2022 | Details |
| A50298 | 35439567 | J Hepatol | Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: A randomised, open-label phase II trial. | 2022 | Details |
| A50301 | 35438253 | Hepatol Commun | Interaction of metabolic dysfunction-associated fatty liver disease and nonalcoholic fatty liver disease with advanced fibrosis in the death and intubation of patients hospitalized with coronavirus disease 2019. | 2022 | Details |
| A50302 | 35438166 | Clin Sci (Lond) | Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis. | 2022 | Details |
| A50305 | 35437902 | J Diabetes Investig | Combined evaluation of Fibrosis-4 index and fatty liver for stratifying the risk for diabetes mellitus. | 2022 | Details |
| A50306 | 35437549 | Food Funct | L-Methionine supplementation attenuates high-fat fructose diet-induced non-alcoholic steatohepatitis by modulating lipid metabolism, fibrosis, and inflammation in rats. | 2022 | Details |
| A50308 | 35436984 | Cell Death Dis | B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36. | 2022 | Details |
| A50309 | 35436676 | Eur J Cancer | An elevated FIB-4 score is associated with an increased incidence of liver cancer: A longitudinal analysis among 248,224 outpatients in Germany. | 2022 | Details |
| A50311 | 35436629 | Biochem Biophys Res Commun | CircRNA608-microRNA222-PINK1 axis regulates the mitophagy of hepatic stellate cells in NASH related fibrosis. | 2022 | Details |
| A50312 | 35436624 | Clin Gastroenterol Hepatol | Screening HIV Patients at Risk for NAFLD Using MRI-PDFF and Transient Elastography: A European Multicenter Prospective Study. | 2022 | Details |
| A50314 | 35436057 | Egypt J Immunol | Role of Thymosin Beta 4 in the diagnosis of Nonalcoholic Fatty Liver and its relation to Metabolic Syndrome in Egyptian patients. | 2022 | Details |
| A50315 | 35435283 | NMR Biomed | Ammonium quantification in human plasma by proton nuclear magnetic resonance for staging of liver fibrosis in alcohol-related liver disease and nonalcoholic fatty liver disease. | 2022 | Details |
| A50318 | 35434848 | J Gastroenterol Hepatol | Association of thyroid autoimmunity with nonalcoholic fatty liver disease in euthyroid middle-aged subjects: A population-based study. | 2022 | Details |
| A50321 | 35434590 | JHEP Rep | Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease. | 2022 | Details |