Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Thioctic acid26 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02739 | 34264552 | Vopr Pitan | [Pathogenetic mechanisms for the development of hematological disorders in induced fatty liver disease in Wistar rats and assessment of the regulatory effects of carnosine and α-lipoic acid]. | 2021 | Details |
| A02910 | 34200615 | Nutrients | Lipoic Acid Exacerbates Oxidative Stress and Lipid Accumulation in the Liver of Wistar Rats Fed a Hypercaloric Choline-Deficient Diet. | 2021 | Details |
| A04061 | 33772908 | Biofactors | The role of biofactors in the prevention and treatment of age-related diseases. | 2021 | Details |
| A05549 | 33211913 | Vopr Pitan | [Effect of carnosine and α-lipoic acid on hepatocyte apoptosis and the cytokine profile in induced fatty liver disease in Wistar rats]. | 2020 | Details |
| A10421 | 31343010 | Food Funct | Oral α-lipoic acid supplementation in patients with non-alcoholic fatty liver disease: effects on adipokines and liver histology features. | 2019 | Details |
| A12140 | 30585337 | J Clin Pharm Ther | The effect of alpha-lipoic acid on inflammatory markers and body composition in obese patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. | 2018 | Details |
| A15109 | 29090431 | J Endocrinol Invest | Modulatory effects of alpha-lipoic acid (ALA) administration on insulin sensitivity in obese PCOS patients. | 2017 | Details |
| A20637 | 25841776 | Free Radic Biol Med | Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. | 2015 | Details |
| A21653 | 25152027 | Acta Pharmacol Sin | Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice. | 2014 | Details |
| A22715 | 24361606 | Biochim Biophys Acta | Lipoic acid prevents fructose-induced changes in liver carbohydrate metabolism: role of oxidative stress. | 2013 | Details |
| A22761 | 24325457 | J Med Food | The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD. | 2013 | Details |
| A22957 | 24176233 | Nutr Res | Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. | 2013 | Details |
| A23603 | 23634883 | Lipids Health Dis | Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. | 2013 | Details |
| A24472 | 22863080 | Liver Int | α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. | 2012 | Details |
| A24520 | 22819708 | Eur J Pharmacol | Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells. | 2012 | Details |
| A24948 | 22327056 | Obesity (Silver Spring) | Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3. | 2012 | Details |
| A25122 | 22154902 | Life Sci | Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. | 2011 | Details |
| A25209 | 22093454 | Liver Int | Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. | 2011 | Details |
| A45338 | 25123628 | J Nutr Biochem | Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. | 2014 | Details |
| A45531 | 24104204 | Physiol Genomics | Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing. | 2013 | Details |
| A46373 | 19232511 | Arch Biochem Biophys | Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion. | 2009 | Details |
| A46411 | 18972440 | Hepatology | Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. | 2008 | Details |
| A48010 | 26634212 | Biomed Res Int | The Influence of α-Lipoic Acid and Garlic Administration on Biomarkers of Oxidative Stress and Inflammation in Rabbits Exposed to Oxidized Nutrition Oils. | 2015 | Details |
| A48230 | 19148996 | Eksp Klin Gastroenterol | [Efficacy of using alpha-lipoic acid (berlition) in patients with nonalcoholic steatohepatitis]. | 2008 | Details |
| A48946 | 23560159 | Gut Liver | Lipoic Acid prevents the changes of intracellular lipid partitioning by free Fatty Acid. | 2013 | Details |
| A52678 | 23687413 | World J Gastroenterol | Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats. | 2013 | Details |