Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Genetic therapy47 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04639 | 33554867 | Mol Ther | Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice. | 2020 | Details |
| A06999 | 32666604 | FASEB J | Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD. | 2020 | Details |
| A09550 | 31696817 | Curr Gene Ther | Non-coding RNA Associated Competitive Endogenous RNA Regulatory Network: Novel Therapeutic Approach in Liver Fibrosis. | 2019 | Details |
| A10449 | 31333307 | World J Gastroenterol | Hepatocellular carcinoma: Therapeutic advances in signaling, epigenetic and immune targets. | 2019 | Details |
| A10594 | 31278269 | Nat Commun | Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy. | 2019 | Details |
| A10707 | 31227825 | Hum Mol Genet | Recent advances in novel therapies for lipid disorders. | 2019 | Details |
| A10749 | 31211621 | Am J Physiol Endocrinol Metab | Mouse trefoil factor 3 ameliorated high-fat-diet-induced hepatic steatosis via increasing peroxisome proliferator-activated receptor-α-mediated fatty acid oxidation. | 2019 | Details |
| A11672 | 30794635 | PLoS One | NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice. | 2019 | Details |
| A12816 | 30271077 | World J Gastroenterol | Role of microRNAs in alcohol-induced liver disorders and non-alcoholic fatty liver disease. | 2018 | Details |
| A13001 | 30186875 | J Diabetes Res | Enhancement of Adiponectin Ameliorates Nonalcoholic Fatty Liver Disease via Inhibition of FoxO1 in Type I Diabetic Rats. | 2018 | Details |
| A13490 | 29951838 | Biochem Genet | Critical Roles of microRNAs in the Pathogenesis of Fatty Liver: New Advances, Challenges, and Potential Directions. | 2018 | Details |
| A13512 | 29940269 | J Hepatol | Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease. | 2018 | Details |
| A14237 | 29511346 | Oncogene | Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer. | 2018 | Details |
| A15091 | 29101357 | Sci Rep | MicroRNA-27a regulates hepatic lipid metabolism and alleviates NAFLD via repressing FAS and SCD1. | 2017 | Details |
| A18062 | 27377869 | Clin Exp Immunol | MicroRNA-26a-interleukin (IL)-6-IL-17 axis regulates the development of non-alcoholic fatty liver disease in a murine model. | 2016 | Details |
| A19174 | 29889452 | Eksp Klin Gastroenterol | HEPATOPROTECTIVE ROLE OF PLACENTA HYDROLISAT - LAENNEC IN THE TREATMENT OF PATIENTS WITH VIRAL AND PARASITIC LIVER DISEASES. | 2018 | Details |
| A20202 | 26086867 | Hum Gene Ther | Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses. | 2015 | Details |
| A21142 | 25518481 | Eksp Klin Gastroenterol | [Possibilities of using the noninvasive methods of investigating the morphofunctional changes in the liver in patients with non alcoholic steatohepatitis and type 2 diabetes mellitus]. | 2014 | Details |
| A24326 | 22997724 | Klin Med (Mosk) | [Pathogenetic therapy of metabolic syndrome at the stage of visceral lesions]. | 2012 | Details |
| A26321 | 20653983 | Lipids Health Dis | Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats. | 2010 | Details |
| A27134 | 20469674 | Eksp Klin Gastroenterol | [Non-alcoholic fatty liver disease: age peculiarities, breakthrough in pathogenetic therapy]. | 2009 | Details |
| A28683 | 35136065 | Nat Commun | In vivo mitochondrial base editing via adeno-associated viral delivery to mouse post-mitotic tissue. | 2022 | Details |
| A29509 | 33965587 | Cell Mol Gastroenterol Hepatol | Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis. | 2021 | Details |
| A32329 | 28707263 | Drug Deliv Transl Res | Delivery of viral vectors for gene therapy in intimal hyperplasia and restenosis in atherosclerotic swine. | 2018 | Details |
| A33050 | 26784524 | J Immunol Methods | Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking. | 2016 | Details |
| A35446 | 20660248 | J Neurosci | Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. | 2010 | Details |
| A35552 | 20376096 | Gene Ther | PPARgamma is essential for protection against nonalcoholic steatohepatitis. | 2010 | Details |
| A35667 | 19952284 | FASEB J | Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. | 2009 | Details |
| A36240 | 18665160 | Mol Ther | Adeno-associated viral (AAV) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces Abeta deposits in APP + PS1 transgenic mice. | 2008 | Details |
| A36982 | 16779871 | J Gene Med | PhiC31 integrase mediates integration in cultured synovial cells and enhances gene expression in rabbit joints. | 2006 | Details |
| A37294 | 16019264 | Mol Ther | Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice. | 2005 | Details |
| A37302 | 16000060 | Hum Gene Ther | Recombinant adeno-associated viral vectors in the nervous system. | 2005 | Details |
| A37564 | 15352070 | J Gene Med | Hepatocyte-specific gene expression from integrated lentiviral vectors. | 2004 | Details |
| A37825 | 14566362 | Gene Ther | The contralateral effect conferred by intra-articular adenovirus-mediated gene transfer of viral IL-10 is specific to the immunizing antigen. | 2003 | Details |
| A38046 | 12409257 | Mol Ther | Ex vivo gene delivery of IL-1Ra and soluble TNF receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis. | 2002 | Details |
| A44085 | 29867233 | Nat Med | Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates. | 2018 | Details |
| A44698 | 27698966 | Middle East J Dig Dis | New Concepts on Pathogenesis and Diagnosis of Liver Fibrosis; A Review Article. | 2016 | Details |
| A44925 | 26780008 | Curr Opin Lipidol | Gene-based therapies in lipidology: current status and future challenges. | 2015 | Details |
| A45506 | 24240285 | Curr Opin Pediatr | Genetics of nonsyndromic obesity. | 2013 | Details |
| A45513 | 24202306 | Arterioscler Thromb Vasc Biol | Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice. | 2013 | Details |
| A46231 | 20156580 | Int J Biochem Cell Biol | Peroxisome proliferator-activated receptors gamma reverses hepatic nutritional fibrosis in mice and suppresses activation of hepatic stellate cells in vitro. | 2010 | Details |
| A46694 | 16471264 | J Soc Biol | [Experimental modulation of apoptosis: physiopathological and therapeutic targets]. | 2005 | Details |
| A48117 | 22699820 | Cell Mol Life Sci | Peroxisome proliferator-activated receptor-γ as a therapeutic target for hepatic fibrosis: from bench to bedside. | 2012 | Details |
| A49033 | 20704547 | Curr Drug Targets | Heme oxygenase-1 and iron in liver inflammation: a complex alliance. | 2010 | Details |
| A49047 | 20072945 | Curr Opin Mol Ther | Alipogene tiparvovec, an adeno-associated virus encoding the Ser(447)X variant of the human lipoprotein lipase gene for the treatment of patients with lipoprotein lipase deficiency. | 2009 | Details |
| A50197 | 35481220 | Exp Ther Med | Epigenetics in inflammatory liver diseases: A clinical perspective (Review). | 2022 | Details |
| A52931 | 19376605 | J Hepatol | Normoglycemia alone is insufficient to prevent long-term complications of hepatocellular adenoma in glycogen storage disease type Ib mice. | 2009 | Details |