Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00007 | 35256601 | Cell Death Discov | LncRNA MEG3 up-regulates SIRT6 by ubiquitinating EZH2 and alleviates nonalcoholic fatty liver disease. | 2022 | Details |
| A00030 | 35250593 | Front Pharmacol | Combined Use of Bicyclol and Berberine Alleviates Mouse Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A00031 | 35250588 | Front Pharmacol | Platelets in Non-alcoholic Fatty Liver Disease. | 2022 | Details |
| A00041 | 35247611 | Mol Metab | Serum Amyloid A1 Exacerbates Hepatic Steatosis via TLR4 Mediated NF-κB Signaling Pathway. | 2022 | Details |
| A00049 | 35243280 | JHEP Rep | Cellular origins of regenerating liver and hepatocellular carcinoma. | 2021 | Details |
| A00062 | 35235789 | Cell Rep | Distinct hepatic immunological patterns are associated with the progression or inhibition of hepatocellular carcinoma. | 2022 | Details |
| A00082 | 35227772 | Life Sci | sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes. | 2022 | Details |
| A00093 | 35222075 | Front Physiol | MicroRNA-122-5p Inhibition Improves Inflammation and Oxidative Stress Damage in Dietary-Induced Non-alcoholic Fatty Liver Disease Through Targeting FOXO3. | 2022 | Details |
| A00100 | 35220131 | Phytomedicine | 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on SIRT5. | 2022 | Details |
| A00128 | 35212995 | Methods Mol Biol | Single Cell RNA Sequencing in NASH. | 2022 | Details |
| A00148 | 35208265 | Metabolites | Plasma Oxylipin Profile Discriminates Ethnicities in Subjects with Non-Alcoholic Steatohepatitis: An Exploratory Analysis. | 2022 | Details |
| A00157 | 35204710 | Biomolecules | Posttranscriptional Regulation of Insulin Resistance: Implications for Metabolic Diseases. | 2022 | Details |
| A00160 | 35204232 | Antioxidants (Basel) | Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway. | 2022 | Details |
| A00161 | 35204113 | Antioxidants (Basel) | Effects of Colchicine in a Rat Model of Diet-Induced Hyperlipidemia. | 2022 | Details |
| A00162 | 35203687 | Biomedicines | A Novel 2-Hit Zebrafish Model to Study Early Pathogenesis of Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A00174 | 35198905 | iScience | Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity. | 2022 | Details |
| A00179 | 35196511 | Am J Med Sci | Deciphering the Role of Aquaporins in Metabolic Diseases: A Mini Review. | 2022 | Details |
| A00203 | 35187967 | Exp Biol Med (Maywood) | Iron-accumulating splenocytes may exacerbate non-alcoholic steatohepatitis through the production of proinflammatory cytokines and reactive oxygen species. | 2022 | Details |
| A00213 | 35182670 | J Ethnopharmacol | Gryllus bimaculatus De Geer hydrolysates alleviate lipid accumulation, inflammation, and endoplasmic reticulum stress in palmitic acid-treated human hepatoma G2 cells. | 2022 | Details |
| A00235 | 35172845 | Nutr Metab (Lond) | Effects of exercise on high-fat diet-induced non-alcoholic fatty liver disease and lipid metabolism in ApoE knockout mice. | 2022 | Details |
| A00240 | 35171164 | Food Funct | Tangeretin improves hepatic steatosis and oxidative stress through the Nrf2 pathway in high fat diet-induced nonalcoholic fatty liver disease mice. | 2022 | Details |
| A00251 | 35164657 | Bioengineered | Liraglutide inhibits receptor for advanced glycation end products (RAGE)/reduced form of nicotinamide-adenine dinucleotide phosphate (NAPDH) signaling to ameliorate non-alcoholic fatty liver disease (NAFLD) in vivo and vitro. | 2022 | Details |
| A00252 | 35164326 | Molecules | Hyaluronated and PEGylated Liposomes as a Potential Drug-Delivery Strategy to Specifically Target Liver Cancer and Inflammatory Cells. | 2022 | Details |
| A00255 | 35163991 | Molecules | Sitagliptin Is More Effective Than Gliclazide in Preventing Pro-Fibrotic and Pro-Inflammatory Changes in a Rodent Model of Diet-Induced Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A00256 | 35163881 | Molecules | The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models. | 2022 | Details |
| A00269 | 35159371 | Cells | The Origins of NAFLD: The Potential Implication of Intrauterine Life and Early Postnatal Period. | 2022 | Details |
| A00270 | 35159342 | Cells | The Translational Bridge between Inflammation and Hepatocarcinogenesis. | 2022 | Details |
| A00272 | 35158328 | J Physiol Pharmacol | Current approach to hepatobiliary manifestations in inflammatory bowel disease. | 2022 | Details |
| A00278 | 35154523 | Arch Med Sci | Fibroblast growth factor 21 levels and liver inflammatory biomarkers in obese subjects after weight loss. | 2021 | Details |
| A00284 | 35152673 | Zhonghua Gan Zang Bing Za Zhi | [Mechanism study of the protective effects of selective cyclooxygenase-2 enzyme inhibitors on the liver of rats with type 2 diabetes mellitus combined with nonalcoholic steatohepatitis via Rho/ROCK pathway]. | 2022 | Details |
| A00288 | 35152443 | J Food Sci | Bentong ginger oleoresin mitigates liver injury and modulates gut microbiota in mouse with nonalcoholic fatty liver disease induced by high-fat diet. | 2022 | Details |
| A00308 | 35143415 | Aging (Albany NY) | Hesperidin suppresses ERS-induced inflammation in the pathogenesis of non-alcoholic fatty liver disease. | 2022 | Details |
| A00326 | 35134438 | Life Sci | Fluorene-9-bisphenol exposure decreases locomotor activity and induces lipid-metabolism disorders by impairing fatty acid oxidation in zebrafish. | 2022 | Details |
| A00330 | 35133148 | J Agric Food Chem | Iron Activates cGAS-STING Signaling and Promotes Hepatic Inflammation. | 2022 | Details |
| A00341 | 35127789 | Front Nutr | Lentinan Supplementation Protects the Gut-Liver Axis and Prevents Steatohepatitis: The Role of Gut Microbiota Involved. | 2022 | Details |
| A00342 | 35127372 | Acta Pharm Sin B | The cGAS-STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy. | 2021 | Details |
| A00346 | 35126843 | World J Hepatol | Is there a role of lipid-lowering therapies in the management of fatty liver disease? | 2022 | Details |
| A00358 | 35122118 | Semin Immunopathol | TNF in the liver: targeting a central player in inflammation. | 2022 | Details |
| A00359 | 35121786 | Sci Rep | Pericardial fat, thoracic peri-aortic adipose tissue, and systemic inflammatory marker in nonalcoholic fatty liver and abdominal obesity phenotype. | 2022 | Details |
| A00363 | 35119232 | J Basic Clin Physiol Pharmacol | Is it possible to treat nonalcoholic liver disease using a flavanol-based nutraceutical approach? Basic and clinical data. | 2022 | Details |
| A00367 | 35115947 | Front Pharmacol | Gentiana scabra Restrains Hepatic Pro-Inflammatory Macrophages to Ameliorate Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A00390 | 35104757 | Phytomedicine | Seed oil of Rosa roxburghii Tratt against non-alcoholic fatty liver disease in vivo and in vitro through PPARα/PGC-1α-mediated mitochondrial oxidative metabolism. | 2022 | Details |
| A00395 | 35102146 | Nat Commun | Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis. | 2022 | Details |
| A00401 | 35100585 | Ann Nutr Metab | Influences of vitamin D levels and vitamin D binding protein polymorphisms on non-alcoholic fatty liver disease risk in a Chinese population. | 2022 | Details |
| A00404 | 35100024 | Circulation | Salt-Induced Hepatic Inflammatory Memory Contributes to Cardiovascular Damage Through Epigenetic Modulation of SIRT3. | 2022 | Details |
| A00414 | 35093339 | Life Sci | Endothelial group IVA phospholipase A2 promotes hepatic fibrosis with sinusoidal capillarization in the early stage of non-alcoholic steatohepatitis in mice. | 2022 | Details |
| A00425 | 35089208 | Medicine (Baltimore) | Association between liver stiffness measurement by transient elastography and chronic kidney disease. | 2022 | Details |
| A00440 | 35083304 | Front Cardiovasc Med | Oxidized Lipids: Common Immunogenic Drivers of Non-Alcoholic Fatty Liver Disease and Atherosclerosis. | 2022 | Details |
| A00448 | 35079162 | Eur J Clin Nutr | Inflammatory potential of diet and risk of nonalcoholic fatty liver disease: a prospective cohort study. | 2022 | Details |
| A00458 | 35074921 | Proc Natl Acad Sci U S A | Myeloid cell TBK1 restricts inflammatory responses. | 2022 | Details |
| A00460 | 35072542 | Antioxid Redox Signal | SPECIALIZED PRO-RESOLVING MEDIATORS DERIVED FROM N-3 POLYUNSATURATED FATTY ACIDS: ROLE IN METABOLIC SYNDROME AND RELATED COMPLICATIONS. | 2022 | Details |
| A00462 | 35071330 | Front Mol Biosci | HSD17B13: A Potential Therapeutic Target for NAFLD. | 2022 | Details |
| A00468 | 35070000 | World J Hepatol | Liver manifestations and complications in inflammatory bowel disease: A review. | 2021 | Details |
| A00469 | 35069993 | World J Hepatol | Liver-side of inflammatory bowel diseases: Hepatobiliary and drug-induced disorders. | 2021 | Details |
| A00471 | 35069014 | Genet Res (Camb) | Inflammatory Cytokines, Adipocytokines, and Th17/Treg Balance in Patients with Nonalcoholic Fatty Liver Disease following Administration of Dahuang Zhechong Pills. | 2022 | Details |
| A00490 | 35063810 | Nutrition | Satellite cell content and muscle regeneration in a mouse model of NAFLD. | 2021 | Details |
| A00501 | 35060744 | J Med Chem | Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis. | 2022 | Details |
| A00505 | 35058605 | Eur J Clin Nutr | Effects of a low free sugar diet on the management of nonalcoholic fatty liver disease: a randomized clinical trial. | 2022 | Details |
| A00510 | 35057565 | Nutrients | Switching to Regular Diet Partially Resolves Liver Fibrosis Induced by High-Fat, High-Cholesterol Diet in Mice. | 2022 | Details |
| A00518 | 35054837 | Int J Mol Sci | The Potential Role of Cellular Senescence in Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A00519 | 35054478 | Life (Basel) | Deep Sea Water-Dissolved Organic Matter Intake Improves Hyperlipidemia and Inhibits Thrombus Formation and Vascular Inflammation in High-Fat Diet Hamsters. | 2022 | Details |
| A00526 | 35053205 | Biomolecules | Understanding the Role of the Gut Microbiome and Microbial Metabolites in Non-Alcoholic Fatty Liver Disease: Current Evidence and Perspectives. | 2021 | Details |
| A00533 | 35052765 | Biomedicines | Bifidobacterium bifidum Shows More Diversified Ways of Relieving Non-Alcoholic Fatty Liver Compared with Bifidobacterium adolescentis. | 2021 | Details |
| A00551 | 35048923 | Food Funct | Feeding of cuticles from Tenebrio molitor larvae modulates the gut microbiota and attenuates hepatic steatosis in obese Zucker rats. | 2022 | Details |
| A00558 | 35047114 | World J Diabetes | Thioredoxin interacting protein, a key molecular switch between oxidative stress and sterile inflammation in cellular response. | 2021 | Details |
| A00560 | 35046824 | Front Pharmacol | Limonin Alleviates Non-alcoholic Fatty Liver Disease by Reducing Lipid Accumulation, Suppressing Inflammation and Oxidative Stress. | 2022 | Details |
| A00577 | 35042213 | Pathobiology | Non-Alcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma: Immunohistochemical Assessment of Markers of Cancer Cell Metabolism. | 2022 | Details |
| A00579 | 35041255 | Phytother Res | Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease. | 2022 | Details |
| A00580 | 35040788 | Turk J Gastroenterol | Association Between Neutrophil-to-Lymphocyte Ratio with Inflammatory Activity and Fibrosis in Non-alcoholic Fatty Liver Disease. | 2022 | Details |
| A00585 | 35040007 | Mol Biol Rep | High-fat diet intake ameliorates the expression of hedgehog signaling pathway in adult rat liver. | 2022 | Details |
| A00590 | 35038159 | J Cell Commun Signal | Targeting CCN2 protects against progressive non-alcoholic steatohepatitis in a preclinical model induced by high-fat feeding and type 2 diabetes. | 2022 | Details |
| A00595 | 35035496 | Evid Based Complement Alternat Med | Lanzhang Granules Ameliorate Nonalcoholic Fatty Liver Disease by Regulating the PPARα Signaling Pathway. | 2022 | Details |
| A00610 | 35030194 | PLoS One | Mechanisms of liver injury in high fat sugar diet fed mice that lack hepatocyte X-box binding protein 1. | 2022 | Details |
| A00620 | 35024739 | Rom J Morphol Embryol | Systemic and adipose tissue inflammation in NASH: correlations with histopathological aspects. | 2022 | Details |
| A00625 | 35024053 | Cardiovasc Ther | Serum PCSK9 Correlates with PTX3 and Apolipoproteins B, A1, and C3 Concentrations in Patients with Type 2 Diabetes. | 2021 | Details |
| A00626 | 35023936 | Diabetes Metab Syndr Obes | Diagnostic Value of Neutrophil to Lymphocyte Ratio in Non-Alcoholic Fatty Liver Disease Evaluated Using Transient Elastography (TE) with Controlled Attenuated Parameter (CAP). | 2022 | Details |
| A00634 | 35021057 | Immunity | Inflammation in obesity, diabetes, and related disorders. | 2022 | Details |
| A00647 | 35015019 | Food Funct | Preventive effects of black soybean polyphenols on non-alcoholic fatty liver disease in three different mouse models. | 2022 | Details |
| A00658 | 35013040 | J Oleo Sci | Pink Lotus Essential Oil and Alleviates on Free Fatty Acid Induced Steatosis in HepG2 Cells via PI3K/Akt and NF-κB Pathways. | 2022 | Details |
| A00666 | 35010924 | Nutrients | Lactoferrin Prevents Hepatic Injury and Fibrosis via the Inhibition of NF-κB Signaling in a Rat Non-Alcoholic Steatohepatitis Model. | 2021 | Details |
| A00668 | 35009003 | Int J Mol Sci | Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A00675 | 35006629 | Hepatology | Progressive loss of hepatocyte nuclear factor 4 alpha activity in chronic liver diseases in humans. | 2022 | Details |
| A00687 | 35003513 | Oxid Med Cell Longev | TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization. | 2021 | Details |
| A00695 | 35000120 | Clin J Gastroenterol | The impact of emricasan on chronic liver diseases: current data. | 2022 | Details |
| A00696 | 34999396 | Int Immunopharmacol | Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling. | 2022 | Details |
| A00699 | 34998898 | Mol Cell Endocrinol | Ceramide signaling in the gut. | 2022 | Details |
| A00701 | 34998036 | Int Immunopharmacol | Dapagliflozin improves steatohepatitis in diabetic rats via inhibition of oxidative stress and inflammation. | 2022 | Details |
| A00717 | 34990887 | Cell Mol Gastroenterol Hepatol | Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis. | 2022 | Details |
| A00719 | 34990473 | PLoS One | Depressive symptoms in non-alcoholic fatty liver disease are identified by perturbed lipid and lipoprotein metabolism. | 2022 | Details |
| A00726 | 34988202 | Ann Transl Med | Y-box binding protein 1 regulates liver lipid metabolism by regulating the Wnt/β-catenin signaling pathway. | 2021 | Details |
| A00738 | 34983596 | Chin Med | Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages. | 2022 | Details |
| A00739 | 34983354 | Endocr Metab Immune Disord Drug Targets | Increasing risk factors of non-alcoholic fatty liver disease, a look into chronic periodontitis and insulin resistance. | 2022 | Details |
| A00749 | 34981106 | Food Funct | Supplementation with cyanidin and delphinidin mitigates high fat diet-induced endotoxemia and associated liver inflammation in mice. | 2022 | Details |
| A00751 | 34980375 | Food Res Int | Exploring the potential mechanism of Rhodomyrtus tomentosa (Ait.) Hassk fruit phenolic rich extract on ameliorating nonalcoholic fatty liver disease by integration of transcriptomics and metabolomics profiling. | 2021 | Details |
| A00754 | 34979142 | Toxicol Appl Pharmacol | Scopoletin and umbelliferone protect hepatocytes against palmitate- and bile acid-induced cell death by reducing endoplasmic reticulum stress and oxidative stress. | 2021 | Details |
| A00774 | 34972203 | J Crohns Colitis | Inflammatory Bowel Disease-associated Fatty Liver Disease: the Potential Effect of Biologic Agents. | 2022 | Details |
| A00775 | 34971904 | Biochem Biophys Res Commun | Hepatoprotective effects of gemigliptin and empagliflozin in a murine model of diet-induced non-alcoholic fatty liver disease. | 2021 | Details |
| A00787 | 34966475 | Oxid Med Cell Longev | Structural and Functional Modulation of Gut Microbiota by Jiangzhi Granules during the Amelioration of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00788 | 34966296 | Front Psychiatry | Interaction Mechanisms Between Major Depressive Disorder and Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A00793 | 34965565 | Probl Radiac Med Radiobiol | SUBCLINICAL INFLAMMATION IN NON/ALCOHOLIC FATTY LIVER DISEASE AT THE REMOTE PERIOD AFTER THE CHORNOBYL ACCIDENT. | 2021 | Details |