Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00018 | 35252260 | Front Med (Lausanne) | Intermittent Hypoxia Rewires the Liver Transcriptome and Fires up Fatty Acids Usage for Mitochondrial Respiration. | 2022 | Details |
| A00050 | 35243111 | Transl Gastroenterol Hepatol | Palm tocotrienol rich fraction with palm kernel oil supplementation prevents development of liver steatosis in high fat diet ICR mice. | 2022 | Details |
| A00054 | 35241921 | J Inflamm Res | Reduction of Hepatic Steatosis, Oxidative Stress, Inflammation, Ballooning and Insulin Resistance After Therapy with Safranal in NAFLD Animal Model: A New Approach. | 2022 | Details |
| A00072 | 35230646 | Neurochem Res | Non-alcoholic Fatty Liver Disease: Also a Disease of the Brain? A Systematic Review of the Preclinical Evidence. | 2022 | Details |
| A00082 | 35227772 | Life Sci | sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes. | 2022 | Details |
| A00092 | 35222799 | Oxid Med Cell Longev | 4-Octyl Itaconate Prevents Free Fatty Acid-Induced Lipid Metabolism Disorder through Activating Nrf2-AMPK Signaling Pathway in Hepatocytes. | 2022 | Details |
| A00093 | 35222075 | Front Physiol | MicroRNA-122-5p Inhibition Improves Inflammation and Oxidative Stress Damage in Dietary-Induced Non-alcoholic Fatty Liver Disease Through Targeting FOXO3. | 2022 | Details |
| A00095 | 35221291 | J Pharmacol Exp Ther | Resveratrol attenuates HFD-induced hepatic lipotoxicity by up-regulating Bmi-1 expression. | 2022 | Details |
| A00100 | 35220131 | Phytomedicine | 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-D-glucoside ameliorates NAFLD via attenuating hepatic steatosis through inhibiting mitochondrial dysfunction dependent on SIRT5. | 2022 | Details |
| A00116 | 35216100 | Int J Mol Sci | Dysregulation of S-adenosylmethionine Metabolism in Nonalcoholic Steatohepatitis Leads to Polyamine Flux and Oxidative Stress. | 2022 | Details |
| A00147 | 35208513 | Medicina (Kaunas) | Evaluation of Dose-Dependent Obesity and Diabetes-Related Complications of Water Chestnut (Fruit of Trapa japonica) Extracts in Type II Obese Diabetic Mice Induced by 45% Kcal High-Fat Diet. | 2022 | Details |
| A00160 | 35204232 | Antioxidants (Basel) | Dietary Selenium Alleviated Mouse Liver Oxidative Stress and NAFLD Induced by Obesity by Regulating the KEAP1/NRF2 Pathway. | 2022 | Details |
| A00161 | 35204113 | Antioxidants (Basel) | Effects of Colchicine in a Rat Model of Diet-Induced Hyperlipidemia. | 2022 | Details |
| A00179 | 35196511 | Am J Med Sci | Deciphering the Role of Aquaporins in Metabolic Diseases: A Mini Review. | 2022 | Details |
| A00183 | 35195377 | Minerva Endocrinol (Torino) | Inflammation is associated with impairment of oxidative status, carbohydrate and lipid metabolism in type 2 diabetes complicated by non-alcoholic fatty liver disease. | 2022 | Details |
| A00203 | 35187967 | Exp Biol Med (Maywood) | Iron-accumulating splenocytes may exacerbate non-alcoholic steatohepatitis through the production of proinflammatory cytokines and reactive oxygen species. | 2022 | Details |
| A00206 | 35187020 | Front Nutr | Association of Serum Vitamin C With NAFLD and MAFLD Among Adults in the United States. | 2022 | Details |
| A00207 | 35186807 | Can J Gastroenterol Hepatol | Therapeutic Effects of Milk Thistle (Silybum marianum L.) and Artichoke (Cynara scolymus L.) on Nonalcoholic Fatty Liver Disease in Type 2 Diabetic Rats. | 2022 | Details |
| A00240 | 35171164 | Food Funct | Tangeretin improves hepatic steatosis and oxidative stress through the Nrf2 pathway in high fat diet-induced nonalcoholic fatty liver disease mice. | 2022 | Details |
| A00251 | 35164657 | Bioengineered | Liraglutide inhibits receptor for advanced glycation end products (RAGE)/reduced form of nicotinamide-adenine dinucleotide phosphate (NAPDH) signaling to ameliorate non-alcoholic fatty liver disease (NAFLD) in vivo and vitro. | 2022 | Details |
| A00253 | 35164140 | Molecules | A Comparison of the Gene Expression Profiles of Non-Alcoholic Fatty Liver Disease between Animal Models of a High-Fat Diet and Methionine-Choline-Deficient Diet. | 2022 | Details |
| A00275 | 35154670 | Food Sci Nutr | The effect of Spirulina sauce, as a functional food, on cardiometabolic risk factors, oxidative stress biomarkers, glycemic profile, and liver enzymes in nonalcoholic fatty liver disease patients: A randomized double-blinded clinical trial. | 2021 | Details |
| A00304 | 35144052 | Redox Biol | The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities. | 2022 | Details |
| A00333 | 35132345 | Oxid Med Cell Longev | Differentially Expressed Hepatic Genes Revealed by Transcriptomics in Pigs with Different Liver Lipid Contents. | 2022 | Details |
| A00341 | 35127789 | Front Nutr | Lentinan Supplementation Protects the Gut-Liver Axis and Prevents Steatohepatitis: The Role of Gut Microbiota Involved. | 2022 | Details |
| A00363 | 35119232 | J Basic Clin Physiol Pharmacol | Is it possible to treat nonalcoholic liver disease using a flavanol-based nutraceutical approach? Basic and clinical data. | 2022 | Details |
| A00378 | 35111461 | Cureus | Factors That Predict the Progression of Non-alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A00390 | 35104757 | Phytomedicine | Seed oil of Rosa roxburghii Tratt against non-alcoholic fatty liver disease in vivo and in vitro through PPARα/PGC-1α-mediated mitochondrial oxidative metabolism. | 2022 | Details |
| A00460 | 35072542 | Antioxid Redox Signal | SPECIALIZED PRO-RESOLVING MEDIATORS DERIVED FROM N-3 POLYUNSATURATED FATTY ACIDS: ROLE IN METABOLIC SYNDROME AND RELATED COMPLICATIONS. | 2022 | Details |
| A00461 | 35072021 | JHEP Rep | Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance. | 2021 | Details |
| A00479 | 35067233 | Nutr Res Rev | MITOCHONDRIAL DYSFUNCTION AND EPIGENETICS UNDERLYING THE LINK BETWEEN EARLY-LIFE NUTRITION AND NON-ALCOHOLIC FATTY LIVER DISEASE. | 2022 | Details |
| A00490 | 35063810 | Nutrition | Satellite cell content and muscle regeneration in a mouse model of NAFLD. | 2021 | Details |
| A00510 | 35057565 | Nutrients | Switching to Regular Diet Partially Resolves Liver Fibrosis Induced by High-Fat, High-Cholesterol Diet in Mice. | 2022 | Details |
| A00519 | 35054478 | Life (Basel) | Deep Sea Water-Dissolved Organic Matter Intake Improves Hyperlipidemia and Inhibits Thrombus Formation and Vascular Inflammation in High-Fat Diet Hamsters. | 2022 | Details |
| A00524 | 35053404 | Cells | Role of Mitochondrial Cytochrome P450 2E1 in Healthy and Diseased Liver. | 2022 | Details |
| A00539 | 35052640 | Antioxidants (Basel) | Phytochemicals from the Cocoa Shell Modulate Mitochondrial Function, Lipid and Glucose Metabolism in Hepatocytes via Activation of FGF21/ERK, AKT, and mTOR Pathways. | 2022 | Details |
| A00541 | 35052595 | Antioxidants (Basel) | Oxidative Stress Is a Key Modulator in the Development of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00543 | 35052573 | Antioxidants (Basel) | Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig. | 2021 | Details |
| A00544 | 35052547 | Antioxidants (Basel) | Preventive Effects of β-Cryptoxanthin, a Potent Antioxidant and Provitamin A Carotenoid, on Lifestyle-Related Diseases-A Central Focus on Its Effects on Non-Alcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A00550 | 35050176 | Metabolites | Lentinan Protects against Nonalcoholic Fatty Liver Disease by Reducing Oxidative Stress and Apoptosis via the PPARα Pathway. | 2022 | Details |
| A00558 | 35047114 | World J Diabetes | Thioredoxin interacting protein, a key molecular switch between oxidative stress and sterile inflammation in cellular response. | 2021 | Details |
| A00560 | 35046824 | Front Pharmacol | Limonin Alleviates Non-alcoholic Fatty Liver Disease by Reducing Lipid Accumulation, Suppressing Inflammation and Oxidative Stress. | 2022 | Details |
| A00564 | 35045647 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of sodium butyrate in metabolic-associated fatty liver disease]. | 2021 | Details |
| A00584 | 35040119 | Eur J Clin Invest | Fatty kidney: A possible future for chronic kidney disease research. | 2022 | Details |
| A00588 | 35038955 | Bioengineered | MicroRNA-665-3p exacerbates nonalcoholic fatty liver disease in mice. | 2022 | Details |
| A00593 | 35036572 | Biol Methods Protoc | Preparation of fatty acid solutions exerts significant impact on experimental outcomes in cell culture models of lipotoxicity. | 2021 | Details |
| A00611 | 35029891 | Medicine (Baltimore) | Characteristics of peripheral blood Gamma-glutamyl transferase in different liver diseases. | 2022 | Details |
| A00640 | 35018684 | Phytother Res | Banana green peels extract protects against nonalcoholic fatty liver disease in high-fat-fed mice through modulation of lipid metabolism and inflammation. | 2022 | Details |
| A00647 | 35015019 | Food Funct | Preventive effects of black soybean polyphenols on non-alcoholic fatty liver disease in three different mouse models. | 2022 | Details |
| A00669 | 35008925 | Int J Mol Sci | Non-Alcoholic Steatohepatitis (NASH) and Organokines: What Is Now and What Will Be in the Future. | 2022 | Details |
| A00677 | 35005749 | Food Funct | Protective effect of orange essential oil on the formation of non-alcoholic fatty liver disease caused by high-fat diet. | 2022 | Details |
| A00683 | 35004861 | Front Mol Biosci | Beyond the Liver: Liver-Eye Communication in Clinical and Experimental Aspects. | 2021 | Details |
| A00685 | 35004133 | Anal Cell Pathol (Amst) | MicroRNA-137-3p Improves Nonalcoholic Fatty Liver Disease through Activating AMPKα. | 2021 | Details |
| A00691 | 35002729 | Front Pharmacol | Mitochondrial Targeting Therapeutics: Promising Role of Natural Products in Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A00696 | 34999396 | Int Immunopharmacol | Liensinine alleviates high fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) through suppressing oxidative stress and inflammation via regulating TAK1/AMPK signaling. | 2022 | Details |
| A00701 | 34998036 | Int Immunopharmacol | Dapagliflozin improves steatohepatitis in diabetic rats via inhibition of oxidative stress and inflammation. | 2022 | Details |
| A00706 | 34994824 | Naunyn Schmiedebergs Arch Pharmacol | The crucial role of oxidative stress in non-alcoholic fatty liver disease-induced male reproductive toxicity: the ameliorative effects of Iranian indigenous probiotics. | 2022 | Details |
| A00718 | 34990729 | Toxicol Appl Pharmacol | Whole life exposure to low dose cadmium alters diet-induced NAFLD. | 2022 | Details |
| A00738 | 34983596 | Chin Med | Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages. | 2022 | Details |
| A00749 | 34981106 | Food Funct | Supplementation with cyanidin and delphinidin mitigates high fat diet-induced endotoxemia and associated liver inflammation in mice. | 2022 | Details |
| A00751 | 34980375 | Food Res Int | Exploring the potential mechanism of Rhodomyrtus tomentosa (Ait.) Hassk fruit phenolic rich extract on ameliorating nonalcoholic fatty liver disease by integration of transcriptomics and metabolomics profiling. | 2021 | Details |
| A00754 | 34979142 | Toxicol Appl Pharmacol | Scopoletin and umbelliferone protect hepatocytes against palmitate- and bile acid-induced cell death by reducing endoplasmic reticulum stress and oxidative stress. | 2021 | Details |
| A00775 | 34971904 | Biochem Biophys Res Commun | Hepatoprotective effects of gemigliptin and empagliflozin in a murine model of diet-induced non-alcoholic fatty liver disease. | 2021 | Details |
| A00793 | 34965565 | Probl Radiac Med Radiobiol | SUBCLINICAL INFLAMMATION IN NON/ALCOHOLIC FATTY LIVER DISEASE AT THE REMOTE PERIOD AFTER THE CHORNOBYL ACCIDENT. | 2021 | Details |
| A00795 | 34964604 | Biomacromolecules | Construction of Glycogen-Based Nanoparticles Loaded with Resveratrol for the Alleviation of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A00801 | 34960036 | Nutrients | Protective Effects of Sesamol against Liver Oxidative Stress and Inflammation in High-Fat Diet-Induced Hepatic Steatosis. | 2021 | Details |
| A00805 | 34959901 | Nutrients | Role and Treatment of Insulin Resistance in Patients with Chronic Kidney Disease: A Review. | 2021 | Details |
| A00824 | 34956386 | Evid Based Complement Alternat Med | Procyanidin B2 Alleviates Palmitic Acid-Induced Injury in HepG2 Cells via Endoplasmic Reticulum Stress Pathway. | 2021 | Details |
| A00831 | 34954593 | Eur J Med Chem | Discovery of new and highly effective quadruple FFA1 and PPARα/γ/δ agonists as potential anti-fatty liver agents. | 2021 | Details |
| A00832 | 34954499 | Redox Biol | Inhibition of GCN2 alleviates hepatic steatosis and oxidative stress in obese mice: Involvement of NRF2 regulation. | 2021 | Details |
| A00834 | 34954022 | Free Radic Biol Med | Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage. | 2021 | Details |
| A00851 | 34948020 | Int J Mol Sci | The New Therapeutic Approaches in the Treatment of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00880 | 34943134 | Antioxidants (Basel) | Hepatoprotective Effect of Bee Bread in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Rats: Impact on Oxidative Stress and Inflammation. | 2021 | Details |
| A00882 | 34943103 | Antioxidants (Basel) | Association of Serum Bilirubin and Functional Variants of Heme Oxygenase 1 and Bilirubin UDP-Glucuronosyl Transferase Genes in Czech Adult Patients with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A00898 | 34935645 | JCI Insight | Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring. | 2021 | Details |
| A00914 | 34931979 | Curr Mol Med | Endogenous liver protections against lipotoxicity and oxidative stress to avoid the progression of non-alcoholic fatty liver to more serious disease. | 2022 | Details |
| A00924 | 34928287 | Food Funct | Identification of mitochondria-related hub genes in sarcopenia and functional regulation of MFG-E8 on ROS-mediated mitochondrial dysfunction and cell cycle arrest. | 2022 | Details |
| A00932 | 34925237 | Front Endocrinol (Lausanne) | Current and Potential Therapies Targeting Inflammation in NASH. | 2021 | Details |
| A00947 | 34922572 | Nutr Metab (Lond) | Alleviating the effect of quinoa and the underlying mechanism on hepatic steatosis in high-fat diet-fed rats. | 2021 | Details |
| A00971 | 34915054 | J Hepatol | A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH. | 2021 | Details |
| A00973 | 34914973 | Exp Mol Pathol | TGF-β1 signaling can worsen NAFLD with liver fibrosis backdrop. | 2021 | Details |
| A00988 | 34909410 | Psoriasis (Auckl) | Non-Alcoholic Fatty Liver Disease (NAFLD) in Patients with Psoriasis: A Review of the Hepatic Effects of Systemic Therapies. | 2021 | Details |
| A01006 | 34904613 | Food Funct | Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin. | 2022 | Details |
| A01011 | 34904026 | World J Hepatol | Promising diagnostic biomarkers of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: From clinical proteomics to microbiome. | 2021 | Details |
| A01021 | 34901163 | Front Mol Biosci | The Role of Notch Signaling Pathway in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01040 | 34893685 | Acta Pharmacol Sin | The miR-23-27-24 cluster: an emerging target in NAFLD pathogenesis. | 2021 | Details |
| A01047 | 34890043 | Eur J Clin Invest | The advantages of physical exercise as a preventive strategy against NAFLD in postmenopausal women. | 2022 | Details |
| A01062 | 34884447 | Int J Mol Sci | Intracellular Exposure Dose-Associated Susceptibility of Steatotic Hepatocytes to Metallic Nanoparticles. | 2021 | Details |
| A01066 | 34882306 | FEBS J | p62/SQSTM1 in liver diseases: the usual suspect with multifarious identities. | 2021 | Details |
| A01067 | 34881510 | Pediatr Obes | The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial. | 2021 | Details |
| A01082 | 34874519 | Chin J Integr Med | Lycium barbarum Polysaccharides Promotes Mitochondrial Biogenesis and Energy Balance in a NAFLD Cell Model. | 2021 | Details |
| A01095 | 34870551 | Pharm Biol | Ellagic acid protects against non-alcoholic fatty liver disease in streptozotocin-diabetic rats by activating AMPK. | 2022 | Details |
| A01096 | 34870139 | Metabol Open | Protective effects of cerium oxide nanoparticles in non-alcoholic fatty liver disease (NAFLD) and carbon tetrachloride-induced liver damage in rats: Study on intestine and liver. | 2021 | Details |
| A01097 | 34870138 | Metabol Open | Metabolic causes and consequences of nonalcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A01111 | 34866849 | J Clin Exp Hepatol | Tobacco, Cigarettes, and the Liver: The Smoking Gun. | 2021 | Details |
| A01138 | 34858322 | Front Endocrinol (Lausanne) | The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review. | 2021 | Details |
| A01150 | 34853966 | Bull Exp Biol Med | Knockdown of Sirt1 Gene in Mice Results in Lipid Accumulation in the Liver Mediated via PGC-1α-Induced Mitochondrial Dysfunction and Oxidative Stress. | 2021 | Details |
| A01161 | 34848360 | J Ethnopharmacol | Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model. | 2021 | Details |
| A01167 | 34847213 | Food Funct | Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence. | 2021 | Details |
| A01207 | 34829753 | Biomedicines | Genetics, Immunity and Nutrition Boost the Switching from NASH to HCC. | 2021 | Details |