Repositioning Candidate Details
| Candidate ID: | R0116 |
| Source ID: | DB00326 |
| Source Type: | approved |
| Compound Type: | small molecule |
| Compound Name: | Calcium glucoheptonate |
| Synonyms: | calcium (2ξ)-D-gluco-heptonate; calcium bis[(2ξ)-D-glycero-D-gulo-heptonate]; calcium bis[(2ξ)-D-glycero-D-ido-heptonate]; calcium bis[(3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate]; Calcium gluceptate; Calcium glucoheptonate; Calcium glucoheptonate (1:2) |
| Molecular Formula: | C14H26CaO16 |
| SMILES: | [Ca++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O |
| Structure: |
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| DrugBank Description: | Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. Calcium is also needed for the heart, muscles, and nervous system to work properly. |
| CAS Number: | 29039-00-7 |
| Molecular Weight: | 490.425 |
| DrugBank Indication: | For treatment of mild hypocalcemia due to neonatal tetany, tetany due to parathyroid deficiency or vitamin D deficiency, and alkalosis, as prophylaxis of hypocalcemia during exchange transfusions, in the treatment of intestinal malabsorption, and to replenish electrolytes. |
| DrugBank Pharmacology: | Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones. Calcium is also needed for the heart, muscles, and nervous system to work properly. The bones serve as a storage site for the body's calcium. They are continuously giving up calcium to the bloodstream and then replacing it as the body's need for calcium changes from day to day. When there is not enough calcium in the blood to be used by the heart and other organs, your body will take the needed calcium from the bones. When you eat foods rich in calcium, the calcium will be restored to the bones and the balance between your blood and bones will be maintained. |
| DrugBank MoA: | Calcium gluceptate replenishes the deminished levels of calcium in the body, returning them to normal levels. |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I02 | 5113 | Nutritional deficiency disease | A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content. https://medlineplus.gov/malnutrition.html | disease of metabolism/acquired metabolic disease/nutrition disease | Details |