Repositioning Candidate Details
| Candidate ID: | R1321 |
| Source ID: | DB10552 |
| Source Type: | approved |
| Compound Type: | biotech |
| Compound Name: | Peach |
| Synonyms: | PEACH ALLERGENIC EXTRACT |
| Molecular Formula: | -- |
| SMILES: | -- |
| DrugBank Description: | Peach allergenic extract is used in allergenic testing. |
| CAS Number: | -- |
| Molecular Weight: | |
| DrugBank Indication: | For the treatment of Pneumococcal pneumonia due to susceptible strains and group A beta-hemolytic streptococcal infections of the upper respiratory tract. |
| DrugBank Pharmacology: | Troleandomycin is a macrolide antibiotic that is similar to erythromycin. It is active in vitro against the following gram-positive organisms: *Streptococcus pyogenes* and *Diplococcus pneumoniae*. |
| DrugBank MoA: | Troleandomycin acts by penetrating the bacterial cell membrane and reversibly binding to the 50 S subunit of bacterial ribosomes or near the "P" or donor site so that binding of tRNA (transfer RNA) to the donor site is blocked. Translocation of peptides from the "A" or acceptor site to the "P" or donor site is prevented, and subsequent protein synthesis is inhibited. |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I01 | 552 | Pneumonia | A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing. http://en.wikipedia.org/wiki/Pneumonia | disease of anatomical entity/respiratory system disease/ lower respiratory tract disease/lung disease | Details |