Repositioning Candidate Details
| Candidate ID: | R0602 |
| Source ID: | DB04377 |
| Source Type: | experimental |
| Compound Type: | small molecule |
| Compound Name: | Meglutol |
| Synonyms: | 3-hydroxy-3-methylglutaric acid; Dicrotalic acid |
| Molecular Formula: | C6H10O5 |
| SMILES: | CC(O)(CC(O)=O)CC(O)=O |
| Structure: |
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| DrugBank Description: | An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol. |
| CAS Number: | 503-49-1 |
| Molecular Weight: | 162.1406 |
| DrugBank Indication: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase |
| Inclusion Criteria: | Target associated |
