Repositioning Candidate Details
| Candidate ID: | R0603 |
| Source ID: | DB04447 |
| Source Type: | experimental |
| Compound Type: | small molecule |
| Compound Name: | 1,4-Dithiothreitol |
| Synonyms: | 2,3-dihydroxy-1,4-dithiobutane |
| Molecular Formula: | C4H10O2S2 |
| SMILES: | O[C@@H](CS)[C@@H](O)CS |
| Structure: |
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| DrugBank Description: | A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. |
| CAS Number: | 3483-12-3 |
| Molecular Weight: | 154.251 |
| DrugBank Indication: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | Protease synthase and sporulation negative regulatory protein PAI 1; Holo-[acyl-carrier-protein] synthase; Histidinol dehydrogenase; Shikimate dehydrogenase; Galectin-1; Calcium/calmodulin-dependent protein kinase type II subunit alpha; 50S ribosomal protein L27; Retinal dehydrogenase 1; Organic hydroperoxide resistance protein; 3-carboxy-cis,cis-muconate cycloisomerase; Transient receptor potential cation channel subfamily M member 7; Unsaturated glucuronyl hydrolase; Cyclic pyranopterin monophosphate synthase; C protein alpha-antigen; Mitochondrial peptide methionine sulfoxide reductase; Chaperone protein TorD; Axin-1; Peptidyl-prolyl cis-trans isomerase B; Amylosucrase; Thymidylate synthase; Triosephosphate isomerase; Maleylacetoacetate isomerase; 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Listeriolysin regulatory protein |
| Inclusion Criteria: | Target associated |
