Repositioning Candidate Details
| Candidate ID: | R0607 |
| Source ID: | DB04557 |
| Source Type: | experimental |
| Compound Type: | small molecule |
| Compound Name: | Arachidonic Acid |
| Synonyms: | -- |
| Molecular Formula: | C20H32O2 |
| SMILES: | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O |
| Structure: |
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| DrugBank Description: | An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. |
| CAS Number: | 506-32-1 |
| Molecular Weight: | 304.4669 |
| DrugBank Indication: | -- |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | 14 kDa fatty acid-binding protein; Prostaglandin G/H synthase 1; Peroxisome proliferator-activated receptor alpha; Bile acid receptor ligand; Retinoic acid receptor RXR-alpha |
| Inclusion Criteria: | Target associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T03 | Peroxisome proliferator-activated receptor alpha | PPARA | agonist | Nuclear hormone receptor | Q07869 | PPARA_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| Diseases ID | DO ID | Disease Name | Definition | Class |
|---|