Repositioning Candidate Details
| Candidate ID: | R0792 |
| Source ID: | DB05422 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | OPC-14523 |
| Synonyms: | -- |
| Molecular Formula: | C23H28ClN3O2 |
| SMILES: | COC1=CC=CC2=C1CCC(=O)N2CCCN1CCN(CC1)C1=CC=CC(Cl)=C1 |
| Structure: |
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| DrugBank Description: | OPC-14523 is an antidepressant drug developed by Otsuka America Pharmaceutical. |
| CAS Number: | 145969-30-8 |
| Molecular Weight: | 413.95 |
| DrugBank Indication: | Investigated for use/treatment in bulimia, depression, and obsessive-compulsive disorders. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | OPC-14523 is a serotonin reuptake inhibitor. It treats depression, especially refractory depression, in a mammal, including a human, by administering to the mammal a sigma receptor ligand in combination with an antidepressant agent. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier, a sigma receptor ligand and a serotonin reuptake inhibitor. |
| Targets: | Sodium-dependent serotonin transporter |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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