Repositioning Candidates

Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.

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     Peroxisome proliferator-activated receptor delta
18 records.
Candidate ID Source ID Source Type Compound Type Candidate Name Inclusion Criteria
R0043 DB00132 approved; investigational; nutraceutical small molecule alpha-Linolenic acid Therapeutic strategy associated Details
R0056 DB00159 approved; nutraceutical small molecule Icosapent Therapeutic strategy associated Details
R0112 DB00313 approved; investigational small molecule Valproic acid Therapeutic strategy associated Details
R0134 DB00374 approved; investigational small molecule Treprostinil Therapeutic strategy associated Details
R0212 DB00605 approved; investigational small molecule Sulindac Therapeutic strategy associated Details
R0570 DB02746 experimental small molecule Phthalic Acid Target associated Details
R0582 DB03338 experimental small molecule Heptyl glucoside Target associated Details
R0597 DB04224 approved; investigational; vet_approved small molecule Oleic Acid Target associated Details
R0616 DB04801 experimental small molecule cis-Vaccenic acid Target associated Details
R0727 DB05188 investigational small molecule KD3010 Target associated Details
R0789 DB05416 investigational small molecule Cardarine Target associated Details
R1113 DB07070 experimental small molecule (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid Target associated Details
R1124 DB07691 experimental small molecule 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid Target associated Details
R1127 DB07724 experimental small molecule Indeglitazar Target associated Details
R1134 DB08078 experimental small molecule {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid Target associated Details
R1192 DB09006 experimental small molecule Clinofibrate Target associated Details
R1312 DB09462 approved; investigational small molecule Glycerin Target associated Details
R1497 DB13873 approved small molecule Fenofibric acid Target associated Details