Repositioning Candidates

Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.

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     Thyroid hormone receptor beta
13 records.
Candidate ID Source ID Source Type Compound Type Candidate Name Inclusion Criteria
R0102 DB00279 approved; vet_approved small molecule Liothyronine Target associated Details
R0174 DB00509 approved; investigational small molecule Dextrothyroxine Target associated Details
R0534 DB01583 approved small molecule Liotrix Target associated Details
R0558 DB02106 experimental small molecule [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid Target associated Details
R0577 DB03176 experimental small molecule KB-141 Target associated Details
R0578 DB03181 experimental small molecule 2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione Target associated Details
R0589 DB03604 investigational small molecule Tiratricol Target associated Details
R0593 DB03788 experimental small molecule GC-24 Target associated Details
R0681 DB05035 investigational small molecule Eprotirome Target associated Details
R0729 DB05192 investigational small molecule MB07811 Target associated Details
R1120 DB07425 investigational small molecule Sobetirome Target associated Details
R1135 DB08085 experimental small molecule 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE Target associated Details
R1224 DB09100 approved biotech Thyroid, porcine Target associated Details