Bioactive Compound Details
| Compound ID: | B100000 |
| Source ID: | CHEMBL18797 |
| Source Type: | Small molecule |
| Compound Name: | SULINDAC SULFIDE |
| Synonyms: | CIS-SULINDAC SULFIDE|SULINDAC RELATED COMPOUND C|SULINDAC SULFIDE, (Z)-|SULINDAC SULPHIDE, (Z)-|Sulindac Sulfide|Sulindac sulfide|Z-SULINDAC SULFIDE |
| Molecular Formula: | C20H17FO2S |
| SMILES: | CSc1ccc(/C=C2/C(C)=C(CC(=O)O)c3cc(F)ccc32)cc1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |