Bioactive Compound Details
| Compound ID: | B104133 |
| Source ID: | CHEMBL190 |
| Source Type: | Small molecule |
| Compound Name: | THEOPHYLLINE |
| Synonyms: | ACCURBRON|AEROLATE|AEROLATE III|AEROLATE JR|AEROLATE SR|AQUAPHYLLIN|BRONKODYL|DIMETHYLXANTHINE|DOXOPHYLLINE METABOLITE M3|DURAPHYL|ELIXICON|ELIXOMIN|ELIXOPHYLLIN SR|Elixophyllin|LABID|LANOPHYLLIN|LASMA|NSC-2066|NSC-757346|NUELIN|NUELIN SA|NUELIN SA-250|PRO-VENT|QUIBRON-T|QUIBRON-T/SR|Quibron|Respbid|SLO-BID|SLO-PHYLLIN|SOMOPHYLLIN-CRT|SOMOPHYLLIN-T|SUSTAIRE|T-PHYL|THEO-DUR|THEOBID|THEOBID JR.|THEOCLEAR L.A.-130|THEOCLEAR L.A.-260|THEOCLEAR-100|THEOCLEAR-200|THEOCLEAR-80|THEOGRAD|THEOLAIR|THEOLIXIR|THEOPHYL|THEOPHYL-225|THEOPHYL-SR|THEOPHYLLINE|THEOPHYLLINE ANHYDROUS|THEOPHYLLINE MELTING POINT STANDARD|THEOPHYLLINE MONOHYDRATE|THEOPHYLLINE, ANHYDROUS|THEOPHYLLINE,ANHYDROUS|THEOPHYLLINE-SR|THEOVENT|Theo-24|Theochron|Theocin|Theolair-sr|Theophylline|UNI-DUR|UNIPHYLLIN CONTINUS|Uniphyl |
| Molecular Formula: | C7H8N4O2 |
| SMILES: | Cn1c(=O)c2nc[nH]c2n(C)c1=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |