Bioactive Compound Details
| Compound ID: | B105694 |
| Source ID: | CHEMBL192 |
| Source Type: | Small molecule |
| Compound Name: | SILDENAFIL |
| Synonyms: | APHRODIL|HIP-0908|HIP0908|NIPATRA|PATREX|REVATIO|SILDENAFIL|SILDENAFIL ACTAVIS|SILDENAFIL RATIOPHARM|SILDENAFIL TEVA|Sildenafil|UK-92480|VIAGRA|VIZARSIN |
| Molecular Formula: | C22H30N6O4S |
| SMILES: | CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |