Bioactive Compound Details
| Compound ID: | B109274 |
| Source ID: | CHEMBL20883 |
| Source Type: | Small molecule |
| Compound Name: | TEGAFUR |
| Synonyms: | ATILLON|BMS-200604|CITOFUR|COPAROGIN|EXONAL|FENTAL|FRANROSE|FT-207|FTORAFUR|FULAID|FULFEEL|FURAFLUOR|FUROFUTRAN|FUTRAFUL|J356.722B|LAMAR|LIFRIL|MJF-12264|NEBERK|NITOBANIL|NSC-148958|SINOFLUROL|SUNFURAL|TEFSIEL C|TEGAFUR|TEGAFUR-URACIL|UFTORAL|YOUFUDING |
| Molecular Formula: | C8H9FN2O3 |
| SMILES: | O=c1[nH]c(=O)n(C2CCCO2)cc1F |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |