Bioactive Compound Details
| Compound ID: | B114540 |
| Source ID: | CHEMBL219916 |
| Source Type: | Small molecule |
| Compound Name: | DOMPERIDONE |
| Synonyms: | DOMILIUM|DOMPERIDONE|EVOXIN|MOTILIUM 10|MOTILIUM INSTANTS|Motilium|NSC-299589|NSC-759575|R 33,812|R-33812|VIVADONE |
| Molecular Formula: | C22H24ClN5O2 |
| SMILES: | O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |