Bioactive Compound Details
| Compound ID: | B001151 |
| Source ID: | CHEMBL115 |
| Source Type: | Small molecule |
| Compound Name: | INDINAVIR |
| Synonyms: | CRIXIVAN|Crixivan|INDINAVIR|INDINAVIR ANHYDROUS|INDINAVIR MONOHYDRATE|INDINAVIR SYSTEM SUITABILITY|Indinavir|L-735524|MK-639 |
| Molecular Formula: | C36H47N5O4 |
| SMILES: | CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |