Bioactive Compound Details

Compound ID: B118847
Source ID: CHEMBL3137331
Source Type: Small molecule
Compound Name: DEFACTINIB
Synonyms: DEFACTINIB|PF-04554878|VS-6063
Molecular Formula: C20H21F3N8O3S
SMILES: CNC(=O)c1ccc(Nc2ncc(C(F)(F)F)c(NCc3nccnc3N(C)S(C)(=O)=O)n2)cc1
Molecular Species: NEUTRAL

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T14 Mitogen-activated protein kinase kinase kinase 5 MAP3K5 inhibitor Enzyme Q99683 M3K5_HUMAN Details
T42 Serine/threonine-protein kinase 17B STK17B inhibitor Kinase O94768 ST17B_HUMAN Details