Bioactive Compound Details
| Compound ID: | B127397 |
| Source ID: | CHEMBL364713 |
| Source Type: | Small molecule |
| Compound Name: | NOSCAPINE |
| Synonyms: | (-)-.ALPHA.-NARCOTINE|(-)-NARCOTINE|METHOXYHYDRASTINE|NARCOTINE|NARCOTINUM|NOSCAPINE|NOSCAPINUM|NSC-5366|Tusscapine |
| Molecular Formula: | C22H23NO7 |
| SMILES: | COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |