Bioactive Compound Details
| Compound ID: | B131858 |
| Source ID: | CHEMBL374478 |
| Source Type: | Small molecule |
| Compound Name: | RIFAMPIN |
| Synonyms: | ABRIFAM|BA 411661E|BA-41166E|EREMFAT|L-5103|L-5103 LEPETIT|L-5103-LEPETIT|NIH-10782|NSC-113926|RIFADINE|RIFALDAZINE|RIFALDIN|RIFAMPICIN|RIFAMPICINUM|RIFAMPIN|RIFAMYCIN AMP|RIFAPIAM|RIFAPRODIN|RIFOLDIN|RIMACTAN|Rifadin|Rifampicin|Rimactane |
| Molecular Formula: | C43H58N4O12 |
| SMILES: | CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(/C=N/N5CCN(C)CC5)c(O)c4c3C2=O)NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |