Bioactive Compound Details
| Compound ID: | B132865 |
| Source ID: | CHEMBL389621 |
| Source Type: | Small molecule |
| Compound Name: | HYDROCORTISONE |
| Synonyms: | ACETASOL HC|ACTICORT|AEROSEB-HC|ALA-CORT|ALA-SCALP|ALKINDI SPRINKLE|ALPHADERM|ANFLAM|ANUGESIC HC|ANUSOL HC|ANUSOL PLUS HC|ANUSOL SOOTHING RELIEF|Anucort-HC|Anusol-HC|BALNEOL-HC|BETA-HC|CALMURID HC|CANESTEN HC|CETACORT|CIPRO HC|COBADEX|COLOCORT|CORLAN|CORT-DOME|CORTENEM|CORTENEMA|CORTISOL|Cor-Oticin|Cortef|Cortifoam|Cortril|DAKTACORT|DAKTACORT HYDROCORT|DERMA CARE HYDROCORT|DERMACORT|DERMASPRAY DEMANG|DIODERM|DOME-CORT|ECONACORT|EFCORTELAN P|ELDECORT|EPICORT|EURAX-HC|EURAX-HYDROCORT|EVACORT|EXE-CORT|FLEXICORT|GERMOLOIDS HC|GLYCORT|GREGODERM|H-CORT|HC #1|HC #4|HC (HYDROCORTISONE)|HI-COR|HYDRO-RX|HYDROCORT IN CALAMINE OILY|HYDROCORT IN CETOMACROGOL FOR A|HYDROCORT IN WTE SOFT PARAF|HYDROCORTISONE|HYDROCORTISONE IN ABSORBASE|HYDRODERM|HYDRODERM HC|Hydrocortisone|Hydrocortone|Hytone|JUNGLE FOR|Locoid|MEDICORT|MILDISON LIPOCREAM|Micort-HC|NOGENIC HC|NSC-10483|NUTRACORT|NYBADEX|NYSTAFORM-HC|Neo-Cortef|OTOSEPTIL|OTOSPORIN|Ophthocort|PENECORT|PERINAL|PLENADREN|PROCTOCORT|PROCTOCREAM HC|PROCTOFOAM HC|PROCTOSEDYL|QUINOCORT|SENTIAL HC|STIE-CORT|SYNACORT|TERRA-CORTRIL NYSTATIN|TEXACORT|TIMOCORT|TIMODINE|TOPISONE|TRI-CICATRIN|Terra-Cortril|U-Cort|UNIROID|UNIROID HC|XYLOPROCT|ZENOXONE |
| Molecular Formula: | C21H30O5 |
| SMILES: | C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |