Bioactive Compound Details
| Compound ID: | B134765 |
| Source ID: | CHEMBL406 |
| Source Type: | Small molecule |
| Compound Name: | INDAPAMIDE |
| Synonyms: | ARIFON|BAJATEN|CARDIDE SR|DAMIDE|ETHIBIDE XL|FLUBEST|FLUDEX|FLUDIN|FLUPAMID|INDAFLEX|INDAMIDE|INDAMOL|INDAPAMIDE|INDAXA 2.5|INDIPAM XL|IPAMIX|KYD-041|LORVAS|Lozol|MAPEMID XL|NATRILIX|NATRILIX SR|NATRIX|NINDAXA 2.5|NORANAT|NSC-757075|OPUMIDE 2.5|RAWEL XL|S-1520|SE-1520|TANDIX|TENSAID XL|TERTENSIF|VARBIM XL|VEROXIL |
| Molecular Formula: | C16H16ClN3O3S |
| SMILES: | CC1Cc2ccccc2N1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |