Bioactive Compound Details
| Compound ID: | B134960 |
| Source ID: | CHEMBL407 |
| Source Type: | Small molecule |
| Compound Name: | FLUMAZENIL |
| Synonyms: | ANEXATE|FLUMAZENIL|FLUMAZEPIL|Flumazepil|LANEXAT|MAZICON|Mazicon|NSC-759193|RO 15-1788/000|RO-15-1788|RO-151788|RO-151788000|RO-1722|RO-41-8157|Romazicon |
| Molecular Formula: | C15H14FN3O3 |
| SMILES: | CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |