Bioactive Compound Details
| Compound ID: | B000136 |
| Source ID: | CHEMBL105 |
| Source Type: | Small molecule |
| Compound Name: | MITOMYCIN |
| Synonyms: | AMETYCINE|JELMYTO|MITOCIN-C|MITOMYCIN|MITOMYCIN C|MITOMYCIN-C|MITOSOL|MITOZYTREX|MUAMYCIN|Mutamycin|Mytozytrex|NSC-26980|UGN-101|UGN-102 |
| Molecular Formula: | C15H18N4O5 |
| SMILES: | CO[C@@]12[C@H](COC(N)=O)C3=C(C(=O)C(C)=C(N)C3=O)N1C[C@@H]1N[C@@H]12 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |