Bioactive Compound Details
| Compound ID: | B136692 |
| Source ID: | CHEMBL42 |
| Source Type: | Small molecule |
| Compound Name: | CLOZAPINE |
| Synonyms: | CLOZAPINE|CLOZAPINE (CARACO)|CLOZAPINE (CLOZARIL)|CLOZAPINE (FAZACLO)|CLOZAPINE (IVAX)|CLOZAPINE (MYLAN)|CLOZAPINE (TEVA)|CLOZAPINE (UDL)|CLOZAPINE (VERSACLOZ)|CLOZAPINE RESOLUTION MIXTURE|Clozaril|FAZACLO ODT|Fazaclo|HF 1854|HF-1854|LEPONEX|NSC-757429|VERSACLOZ|ZAPONEX |
| Molecular Formula: | C18H19ClN4 |
| SMILES: | CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |