Bioactive Compound Details
| Compound ID: | B136816 |
| Source ID: | CHEMBL421 |
| Source Type: | Small molecule |
| Compound Name: | SULFASALAZINE |
| Synonyms: | AZULFIDINE EN-TABS|Azulfidine|Azulfidine EN|BENZOSULFA|COLIZINE|NSC-203730|NSC-667219|S.A.S.-500|S.a.s.|SALAZOPYRIN|SALAZOPYRIN E.C.|SALAZOPYRIN-EN|SALAZOSULFAPYRIDINE|SALICYLAZOSULFAPYRIDINE|SAS-500|SULFASALAZINE|SULFASALAZINUM|SULFASALAZOPYRIDINE|SULPHASALAZINE|Salazosulfapyridine|Salicylazosulfapyridine|UCINE |
| Molecular Formula: | C18H14N4O5S |
| SMILES: | O=C(O)c1cc(/N=N/c2ccc(S(=O)(=O)Nc3ccccn3)cc2)ccc1O |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |