Bioactive Compound Details
| Compound ID: | B137799 |
| Source ID: | CHEMBL43064 |
| Source Type: | Small molecule |
| Compound Name: | CINNARIZINE |
| Synonyms: | 516 MD|516-MD|APLACTAN|APLEXAL|ARTATE|CARECIN|CEREBOLAN|CEREPAR|CINAPERAZINE|CINARIZINE|CINAZYN|CINNACET|CINNAGERON|CINNARIZINE|CINNIPIRINE|CORATHIEM|DENAPOL|DIMITRON|EGLEN|FOLCODAL|GIGANTEN|GLANIL|HILACTAN|IXERTOL|KATOSERAN|LABYRIN|MARZINE R.F.|MIDRONAL|MITRONAL|MYLAN TRAVEL SICKNESS|NSC-758400|OLAMIN|PROCESSINE|R 1575|R 516|R-1575|R-516|SEDATROMIN|SEPAN|SIPTAZIN|SPADERIZINE|STUGERON|STUGERON FTE|STUNARONE|STUTGERON|STUTGIN|Stugeron |
| Molecular Formula: | C26H28N2 |
| SMILES: | C(=C/c1ccccc1)\CN1CCN(C(c2ccccc2)c2ccccc2)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |