Bioactive Compound Details
| Compound ID: | B000140 |
| Source ID: | CHEMBL1054 |
| Source Type: | Small molecule |
| Compound Name: | TRICHLORMETHIAZIDE |
| Synonyms: | Metahydrin|NSC-61560|Naqua|TRICHLOREX|TRICHLORMAS|TRICHLORMETHIAZIDE|TRICHLOROMETHIAZIDE|Trichlormethiazide |
| Molecular Formula: | C8H8Cl3N3O4S2 |
| SMILES: | NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |