Bioactive Compound Details

Compound ID: B001401
Source ID: CHEMBL1171837
Source Type: Small molecule
Compound Name: PONATINIB
Synonyms: AP-24534|AP24534|ICLUSIG|PONATINIB
Molecular Formula: C29H27F3N6O
SMILES: Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12
Molecular Species: NEUTRAL

Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T14 Mitogen-activated protein kinase kinase kinase 5 MAP3K5 inhibitor Enzyme Q99683 M3K5_HUMAN Details