Bioactive Compound Details
| Compound ID: | B140182 |
| Source ID: | CHEMBL460291 |
| Source Type: | Small molecule |
| Compound Name: | LACIDIPINE |
| Synonyms: | 3,3'-IMINOBISPROPYLAMINE|3,3'-IMINODIPROPYLAMINE|4-AZAHEPTAMETHYLENEDIAMINE|CALDINE|DIPROPYLAMINE, 3,3'-DIAMINO-|DIPROPYLENETRIAMINE|GR 43659X|GR-43659X|LACIDIPINE|MOLAP|MOTENS|NSC-7773 |
| Molecular Formula: | C26H33NO6 |
| SMILES: | CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1/C=C/C(=O)OC(C)(C)C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |