Bioactive Compound Details
| Compound ID: | B140665 |
| Source ID: | CHEMBL469912 |
| Source Type: | Small molecule |
| Compound Name: | PUROMYCIN |
| Synonyms: | 3123-L|3123L|CL 13,900|CL-13900|GNF-PF-2016|P-638|PUROMYCIN|TCMDC-123493 |
| Molecular Formula: | C22H29N7O5 |
| SMILES: | COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@@H](n3cnc4c(N(C)C)ncnc43)[C@@H]2O)cc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |