Bioactive Compound Details
| Compound ID: | B140730 |
| Source ID: | CHEMBL472 |
| Source Type: | Small molecule |
| Compound Name: | GLYBURIDE |
| Synonyms: | CALABREN|CIRARA|DAONIL|DIABETAMIDE 2.5|DIABETAMIDE 5|Diabeta|EUGLUCON|GLIBENCLAMIDE|GLIBENCLAMIDUM|GLIKEN|GLYBENCLAMIDE|GLYBURIDE|GLYBURIDE (MICRONIZED)|Glynase|Glynase PresTab|HB 419|HB-419|LEDERGLIB|LIBANIL|MALIX|Micronase|NSC-759618|SEMI-DAONIL|U-26,45|U-26,452|U-26452 |
| Molecular Formula: | C23H28ClN3O5S |
| SMILES: | COc1ccc(Cl)cc1C(=O)NCCc1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |