Bioactive Compound Details
| Compound ID: | B141996 |
| Source ID: | CHEMBL490 |
| Source Type: | Small molecule |
| Compound Name: | PAROXETINE |
| Synonyms: | (-)3S,4R-PAROXETINE|ARKETIS|AROTIN|BESITRAM|BRL 29060|BRL-29060|CASBOL|DAPAROX|FG-7051|FROSINOR|MOTIVAN|PAROGEN|PAROXETINE|PAXPAR|Paroxetine|Paxil|Paxil [as hydrochloride]|Pexeva|XETANOR |
| Molecular Formula: | C19H20FNO3 |
| SMILES: | Fc1ccc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)cc1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |