Bioactive Compound Details
| Compound ID: | B142083 |
| Source ID: | CHEMBL493 |
| Source Type: | Small molecule |
| Compound Name: | BROMOCRIPTINE |
| Synonyms: | 2-BROMO-.ALPHA.-ERGOCRYPTINE|BROMERGOCRYPTINE|BROMOCRIPTINE|Bromocriptine|CB-154|ERGOCRYPTINE, 2-BROMO-|PARLODEL|SANDOZ 15-754 |
| Molecular Formula: | C32H40BrN5O5 |
| SMILES: | CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |