Bioactive Compound Details
| Compound ID: | B142362 |
| Source ID: | CHEMBL503 |
| Source Type: | Small molecule |
| Compound Name: | LOVASTATIN |
| Synonyms: | 6.ALPHA.-METHYLCOMPACTIN|Altoprev|C10AA02|L-154803|LOVASTATIN|MEVINACOR|MEVINACOR 10|MEVINACOR 40|MEVINOLIN|MEVLOR|MK-803|MONACOLIN K|Mevacor|NSC-758662|SIMVASTATIN IMPURITY, LOVASTATIN-|SIVLOR |
| Molecular Formula: | C24H36O5 |
| SMILES: | CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |