Bioactive Compound Details
| Compound ID: | B142417 |
| Source ID: | CHEMBL50588 |
| Source Type: | Small molecule |
| Compound Name: | EMETINE |
| Synonyms: | (-)-EMETINE|6',7',10,11-TETRAMETHOXYEMETAN|CEPHAELINE METHYL ETHER|EMETIN|EMETINE|EMETINUM|Emetine|GNF-Pf-196|NSC-33669|TCMDC-125531 |
| Molecular Formula: | C29H40N2O4 |
| SMILES: | CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc21 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |