Bioactive Compound Details
| Compound ID: | B142567 |
| Source ID: | CHEMBL513 |
| Source Type: | Small molecule |
| Compound Name: | CARMUSTINE |
| Synonyms: | BCNU|BECENUN|BISCHLOROETHYL NITROSOUREA|Bicnu|CAMUSTINE|CARMUBRIS|CARMUSTINE|DTI-015|FDA-0345|Gliadel|NSC-409962|SK-27702|SRI-1720 |
| Molecular Formula: | C5H9Cl2N3O2 |
| SMILES: | O=NN(CCCl)C(=O)NCCCl |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |