Bioactive Compound Details
| Compound ID: | B142636 |
| Source ID: | CHEMBL515 |
| Source Type: | Small molecule |
| Compound Name: | CHLORAMBUCIL |
| Synonyms: | AMBOCHLORIN|CB-1348|CHLORAMBUCIL|CHLORAMBUCILUM|CHLORBUTIN|Chlorambucil|ECLORIL|LYMPHOLYSIN|Leukeran|NCI-3088|NSC-3088 |
| Molecular Formula: | C14H19Cl2NO2 |
| SMILES: | O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |