Bioactive Compound Details
| Compound ID: | B142791 |
| Source ID: | CHEMBL521 |
| Source Type: | Small molecule |
| Compound Name: | IBUPROFEN |
| Synonyms: | ACHES-N-PAIN|ADVIL LIQUI-GELS|ADVIL MIGRAINE LIQUI-GELS|ANADIN JOINT PAIN|ANADIN LIQUIFAST|ANADIN PERIOD PAIN RELIEF|ANADIN ULTRA|APSIFEN|APSIFEN-F|ARTHROFEN 200|ARTHROFEN 400|ARTHROFEN 600|Advil|BRUFEN RET|BURANA|CALDOLOR|CAP-PROFEN|CHILDREN'S ADVIL|CHILDREN'S ADVIL-FLAVORED|CHILDREN'S ELIXSURE|CHILDREN'S IBUPROFEN|CHILDREN'S MOTRIN|CO-OP|CODAFEN CONTINUS|CUPROFEN FOR CHILD|CUPROFEN PLUS|DEEP RELIEF|EBUFAC|FEMAFEN|FENBID|FENBID FTE|FENPAED|FEVERFEN|FLEXIMEX|IB-100|IBU-SLO|IBU-TAB|IBU-TAB 200|IBUCALM|IBUDERM|IBUFAC|IBUGEL|IBUGEL FTE|IBULAR|IBULEVE|IBUMED|IBUMETIN|IBUMOUSSE|IBUPRIN|IBUPROFEN|IBUPROFENUM|IBUPROHM|IBUSPRAY|IBUTIME|INABRIN|INFANT'S ADVIL|INOVEN|IP-82|ISISFEN|JUNIFEN|JUNIOR STRENGTH ADVIL|JUNIOR STRENGTH IBUPROFEN|JUNIOR STRENGTH MOTRIN|LIDIFEN|LIDIFEN-F|LOBUFEN|M01AE01|MANDAFEN|MANORFEN|MAXA-GESIC|MEDIPREN|MIDOL|MIDOL LIQUID GELS|MIGRAFEN|MOTRIN IB|MOTRIN MIGRAINE PAIN|Motrin|NOVAPRIN|NSC-256857|NUPRIN|NUROFEN 400|NUROFEN BACK PAIN SR|NUROFEN CHILD|NUROFEN FOR CHILD|NUROFEN PLUS|NUROFEN RECOVERY|NUROFEN SINUS|NUROFEN SOLB|ORBIFEN|PACIFENE|PAXOFEN|PEDEA|PEDIATRIC ADVIL|PHENSIC|PHOR PAIN|PHORPAIN|PHORPAIN MAX STRGH|PROFEN|PROFLEX|PROFLEX SR|RD 13621|RELCOFEN|RIMAFEN|RUFEN|SECLODIN|SUSPREN|TAB-PROFEN|U-18,573|U-18573 |
| Molecular Formula: | C13H18O2 |
| SMILES: | CC(C)Cc1ccc(C(C)C(=O)O)cc1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |