Bioactive Compound Details
| Compound ID: | B142964 |
| Source ID: | CHEMBL527 |
| Source Type: | Small molecule |
| Compound Name: | PIROXICAM |
| Synonyms: | BREXIDOL|CP-16,171|CP-16171|FELDENE 20|FELDENE P|FLAMATROL|Feldene|KENTENE|LARAPAM|NSC-666076|PIROFLAM 10|PIROFLAM 20|PIROXICAM|PIROZIP 10|PIROZIP 20 |
| Molecular Formula: | C15H13N3O4S |
| SMILES: | CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |