Bioactive Compound Details
| Compound ID: | B142988 |
| Source ID: | CHEMBL529 |
| Source Type: | Small molecule |
| Compound Name: | AZITHROMYCIN |
| Synonyms: | ANHYDROUS AZITHROMYCIN|ARUZILINA|AZIROMYCIN|AZITHROCIN|AZITHROMYCIN|AZITHROMYCIN (AS DIHYDRATE)|AZITHROMYCIN ANHYDROUS|AZITHROMYCIN DIHYDRATE|AZITHROMYCIN HYDRATE|AZITHROMYCIN, UNSPECIFIED|AZITHROMYCIN, UNSPECIFIED FORM|AZIWIN|AZYTER|Azasite|CLAMELLE|CP 62993|CP-62,993|CP-62993|DURASITE|HEMOMYCIN|MACROZIT|NSC-758625|SUMAMED|Sumamed|Sunamed|TROZOCINA|XITHRONE|XZ 405|XZ 450|XZ-450|ZITHROMAC|ZMax|ZYTHROMAX|Zithromax |
| Molecular Formula: | C38H72N2O12 |
| SMILES: | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T06 | Glucagon-like peptide 1 receptor | GLP1R | agonist | GPCR | P43220 | GLP1R_HUMAN | Details |