Bioactive Compound Details
| Compound ID: | B143044 |
| Source ID: | CHEMBL53463 |
| Source Type: | Small molecule |
| Compound Name: | DOXORUBICIN |
| Synonyms: | ADRIABLASTIN|Adriamycin|Adriblastina|DOXORUBICIN|Doxil|Doxorubicin|EPIRUBICIN HYDROCHLORIDE IMPURITY, DOXORUBICIN-|HYDROXYDAUNORUBICIN|NSC-123127|NSC-759155|Rubex|VALRUBICIN IMPURITY, DOXORUBICIN |
| Molecular Formula: | C27H29NO11 |
| SMILES: | COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |