Bioactive Compound Details
| Compound ID: | B143499 |
| Source ID: | CHEMBL562 |
| Source Type: | Small molecule |
| Compound Name: | GRISEOFULVIN |
| Synonyms: | FULCIN|FULCIN 125|FULCIN 500|FULSOVIN|FULVICIN P/G|FULVICIN P/G 165|FULVICIN P/G 330|Fulvicin|Fulvicin-P/G|Fulvicin-U/F|GRISACTIN ULTRA|GRISACTIN V|GRISEOFULVIN|GRISEOFULVIN MICROSIZE|GRISEOFULVIN PERMEABILITY DIAMETER|GRISEOFULVIN, MICROCRYSTALLINE|GRISEOFULVIN, MICROSIZE|GRISEOFULVIN, ULTRAMICROCRYSTALLINE|GRISEOFULVIN, ULTRAMICROSIZE|GRISEOFULVIN,MICROSIZE|GRISEOFULVIN,ULTRAMICROSIZE|GRISEOFULVINUM|GRISOL AF|Grifulvin|Grifulvin V|Gris-PEG|Grisactin|Griseofulvin|Grivate|NSC-34533|NSC-755822|ULTRAGRIS-165|ULTRAGRIS-330 |
| Molecular Formula: | C17H17ClO6 |
| SMILES: | COC1=CC(=O)C[C@@H](C)[C@]12Oc1c(Cl)c(OC)cc(OC)c1C2=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |